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Sigma-Aldrich

Sodium iodide

ReagentPlus®, ≥99%

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Linear Formula:
NaI
CAS Number:
Molecular Weight:
149.89
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

vapor density

>1 (vs air)

Quality Level

product line

ReagentPlus®

Assay

≥99%

form

powder

impurities

<1.0% water

pH

6-9 (20 °C, 50 g/L)

mp

661 °C (lit.)

solubility

water: soluble(lit.)

SMILES string

[Na+].[I-]

InChI

1S/HI.Na/h1H;/q;+1/p-1

InChI key

FVAUCKIRQBBSSJ-UHFFFAOYSA-M

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General description

Sodium iodide is an ionic compound that can be prepared by treating sodium hydroxide or sodium carbonate with hydriodic acid. It is a versatile reagent used as an iodide source in organic synthesis.

Application

Sodium iodide can be used as a catalyst :
  • To synthesize α-alkoxylated ketones.
  • For N-tert-butoxy carbonylation of amines.
It can also be used as a reagent for the conversion of aryl amines to aryl iodides.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT RE 1 Oral

Target Organs

Thyroid

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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The Chesapeake Bay Institute technique for the Winkler dissolved oxygen method.
Carpenter JH.
Limnology and Oceanography, 10(1), 141-143 (1965)
Synthetic methods and reactions. 62. Transformations with chlorotrimethylsilane/sodium iodide, a convenient in situ iodotrimethylsilane reagent.
Olah GA, et al.
The Journal of Organic Chemistry, 44(8), 1247-1251 (1979)
Eagleson M.
Concise Encyclopedia Chemistry, 648-648 (1994)
Eagleson M.
Concise Encyclopedia Chemistry, 999-999 (1994)
Anke de Vries et al.
Investigative radiology, 50(4), 297-304 (2015-01-01)
The objective of this study was to investigate the feasibility and the accuracy of spectral computed tomography (spectral CT) to determine the tissue concentrations and localization of high-attenuation, iodine-based contrast agents in mice. Iodine tissue concentrations determined with spectral CT

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