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30417

Sigma-Aldrich

Phosphoric acid

puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥85%

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Synonym(s):
Orthophosphoric acid
Linear Formula:
H3PO4
CAS Number:
Molecular Weight:
98.00
Beilstein:
1921286
EC Number:
MDL number:
PubChem Substance ID:

grade

ACS reagent
puriss. p.a.

Quality Level

Agency

USP/NF
reag. ISO
reag. Ph. Eur.

vapor density

3.4 (vs air)

vapor pressure

2.2 mmHg ( 20 °C)
5 mmHg ( 25 °C)

Assay

≥85%

form

liquid

impurities

reducing impurities, in accordance
residual solvents, in accordance
substances precipitated by ammonia, in accordance
≤0.001% KMnO4 red. matter (as O)
≤0.001% heavy metals (as Pb)
≤0.001% in water insoluble matters
≤0.001% volatile acids (as CH3COOH)

bp

158 °C (lit.)

mp

~40 °C (lit.)

density

1.685 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤2 mg/kg
fluoride (F-): ≤1 mg/kg
nitrate (NO3-): ≤3 mg/kg
phosphite, hypophosphite (as H3PO3): ≤20 mg/kg
phosphite, hypophosphite (as H3PO3): in accordance
sulfate (SO42-): ≤30 mg/kg

cation traces

As: ≤0.5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤5 mg/kg
K: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤0.5 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sb: ≤2 mg/kg
Zn: ≤2 mg/kg

SMILES string

OP(O)(O)=O

suitability

passes test for appearance of solution

InChI

1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)

InChI key

NBIIXXVUZAFLBC-UHFFFAOYSA-N

Gene Information

human ... SRC(6714)

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Other Notes

Concentrated phosphoric acid is approx. 85% H3PO4 (aqueous).
The article number 30417-4X2.5L will be discontinued. Please order the single bottle 30417-2.5L which is physically identical with the same exact specifications.
The article number 30417-4X2.5L-M will be discontinued. Please order the single bottle 30417-2.5L-M which is physically identical with the same exact specifications.
The article number 30417-6X1L will be discontinued. Please order the single bottle 30417-1L which is physically identical with the same exact specifications.
The article number 30417-6X1L-M will be discontinued. Please order the single bottle 30417-1L-M which is physically identical with the same exact specifications.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

危险化学品

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Internal versus external surface active sites in ZSM-5 zeolite: Part 1. Fries rearrangement catalyzed by modified and unmodified H3PO4/ZSM-5.
Ghiaci M, et al.
Applied Catalysis A: General, 298, 32-39 (2006)
P Meneses et al.
Journal of lipid research, 29(5), 679-689 (1988-05-01)
The common phospholipids from biological sources were quantitated using phosphorus-31 nuclear magnetic resonance (NMR) spectroscopy in conjunction with an analytical reagent composed of two parts: 1) 2 ml of reagent chloroform in which was dissolved 0.01-100 mg of crude tissue
D S Marinier et al.
Journal of lipid research, 29(9), 1237-1243 (1988-09-01)
In order to study the lipid composition of human white matter, we have developed a 31P NMR spectroscopy method, which allows the determination and quantitation of the main phospholipids found in biological membranes. The technique is based upon the use
J M Fujitaki et al.
Biochemistry, 20(12), 3658-3664 (1981-06-09)
Phosphorus-31 nuclear magnetic resonance (31P NMR) is used to investigate acid-labile phosphorylation of histone H4. 31P NMR detects phosphorylated histidine residues in in vitro enzymatically phosphorylated H4. The source of kinase is nuclei from either regenerating rat liver or Walker-256
Alessio Ciulli et al.
Journal of medicinal chemistry, 49(16), 4992-5000 (2006-08-04)
Mapping interactions at protein-ligand binding sites is an important aspect of understanding many biological reactions and a key part of drug design. In this paper, we have used a fragment-based approach to probe "hot spots" at the cofactor-binding site of

Protocols

Folic acid or folate is classified as a B vitamin (B9). Folic acid is synthetically produced, and used in fortified foods and supplements. Folate is converted by humans to dihydrofolate (dihydrofolic acid), tetrahydrofolate (tetrahydrofolic acid), and other derivatives, which have various biological activities.

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