N,N-Dimethylformamide

N, N-Dimethylformamide (DMF) is an organic compound commonly used as a reagent as well as a solvent in organic synthesis. It plays multiple roles in various reactions such as formylating agent, dehydrating agent, reducing agent as well as a catalyst.

Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.

Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.

Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.

Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.

DMF can be used as:     

• A formylating agent for organometallic compounds.
• A reactant to prepare Vilsmeier reagent by reacting with phosphorus oxychloride.
• A reagent for amination of aryl chlorides in the presence of potassium t-butoxide.     
• A reducing agent for metal salts to prepare metal colloids.
• A catalyst for the regioselective silylation of unprotected carbohydrates.

DMF can also be used in the following:     

• DMF-Phosgene catalytic system is used to prepare alkyl halides from alcohols.      
• DMF-POCl₃ is used to convert acyclic and cyclic enolizable ketones to β-chloro-α, β-unsaturated aldehydes.
• DMF-POCl₃ is used to synthesize quinoline-3-carbaldehydes from acylanilides.      
• DMF-SOCl₂ combination is used to dehydrate oximes to nitriles.      
• DMF-Ag₂O converts α-bromopropionamides to oxazolidinones.
• DMF is frequently used as a solvent in many chemical reactions, which require a high solvency power.

Solvent for many hydrophobic organic compounds.