319937
N,N-Dimethylformamide
ACS reagent, ≥99.8%
Synonym(s):
DMF, NSC 5356
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About This Item
Linear Formula:
HCON(CH3)2
CAS Number:
Molecular Weight:
73.09
Beilstein:
605365
EC Number:
MDL number:
UNSPSC Code:
12352111
PubChem Substance ID:
NACRES:
NA.07
Grade:
ACS reagent
Assay:
≥99.8%
Bp:
153 °C (lit.)
Vapor pressure:
2.7 mmHg ( 20 °C)
grade
ACS reagent
Quality Level
vapor density
2.5 (vs air)
vapor pressure
2.7 mmHg ( 20 °C)
Assay
≥99.8%
form
liquid
autoignition temp.
833 °F
expl. lim.
15.2 %
dilution
(for analytical testing)
impurities
≤0.0005 meq/g Titr. acid
≤0.003 meq/g Titr. base
≤0.15% water
evapn. residue
≤0.005%
color
clear
APHA: ≤15
refractive index
n20/D 1.430 (lit.)
pH
7 (20 °C, 200 g/L)
bp
153 °C (lit.)
mp
−61 °C (lit.)
density
0.944 g/mL (lit.)
SMILES string
[H]C(=O)N(C)C
InChI
1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
InChI key
ZMXDDKWLCZADIW-UHFFFAOYSA-N
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General description
N, N-Dimethylformamide (DMF) is an organic compound commonly used as a reagent as well as a solvent in organic synthesis. It plays multiple roles in various reactions such as formylating agent, dehydrating agent, reducing agent as well as a catalyst.
Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.
Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.
Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.
Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.
Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.
Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.
Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.
Application
DMF can be used as:
DMF can also be used in the following:
- A formylating agent for organometallic compounds.
- A reactant to prepare Vilsmeier reagent by reacting with phosphorus oxychloride.
- A reagent for amination of aryl chlorides in the presence of potassium t-butoxide.
- A reducing agent for metal salts to prepare metal colloids.
- A catalyst for the regioselective silylation of unprotected carbohydrates.
DMF can also be used in the following:
- DMF-Phosgene catalytic system is used to prepare alkyl halides from alcohols.
- DMF-POCl3 is used to convert acyclic and cyclic enolizable ketones to β-chloro-α, β-unsaturated aldehydes.
- DMF-POCl3 is used to synthesize quinoline-3-carbaldehydes from acylanilides.
- DMF-SOCl2 combination is used to dehydrate oximes to nitriles.
- DMF-Ag2O converts α-bromopropionamides to oxazolidinones.
- DMF is frequently used as a solvent in many chemical reactions, which require a high solvency power.
Solvent for many hydrophobic organic compounds.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
135.5 °F - closed cup
Flash Point(C)
57.5 °C - closed cup
Regulatory Information
危险化学品
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