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Sigma-Aldrich

Sodium acetate

puriss. p.a., ACS reagent, reag. Ph. Eur., anhydrous

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Synonym(s):
Acetic acid sodium salt
Linear Formula:
CH3COONa
CAS Number:
Molecular Weight:
82.03
Beilstein:
3595639
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent
puriss. p.a.

Quality Level

Agency

reag. Ph. Eur.

Assay

≥99.0% (perchloric acid titration)

form

solid

autoignition temp.

1112 °F

impurities

≤0.01% in water soluble matter

loss

≤1% loss on drying, 120 °C

pH

7.5-9.2 (20 °C, 5%)

pKa 

4.76 (acetic acid)

mp

>300 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤0.002%
phosphate (PO43-): ≤0.001%
sulfate (SO42-): ≤0.003%

cation traces

Al: ≤10 mg/kg
Ca: ≤0.005%
Cd: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤0.001%
K: ≤200 mg/kg
Mg: ≤0.002%
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
heavy metals: ≤0.001% (by ICP-OES)

suitability

in accordance for appearance of solution

SMILES string

[Na+].CC([O-])=O

InChI

1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

InChI key

VMHLLURERBWHNL-UHFFFAOYSA-M

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Application

Sodium acetate can be used as a catalyst to synthesize:
  • 1,2-Dihydropyridines by reacting 3-formylchromones, N-nucleophiles, and active methylene molecules.
  • 2(3H)-Furanone derivatives by using cinnamaldehyde and 5-aryl-2(3H) furanone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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A Facile Route to Synthesize 1, 2-Dihydropyridine and 1, 6 Pyrimidinone Analogues from 4-Oxo-4H-Chromene-3-Carbaldehyde
Bari A
Journal of Heterocyclic Chemistry, 53, 461-466 (2016)
Synthesis, Characterization and Photophysical Properties of New 2 (3H) Furanone Derivatives
Soliman M, et al.
Journal of Molecular Structure, 134543-134543 (2022)
Carol L Ladner-Keay et al.
PloS one, 9(6), e98753-e98753 (2014-06-04)
The formation of β-sheet rich prion oligomers and fibrils from native prion protein (PrP) is thought to be a key step in the development of prion diseases. Many methods are available to convert recombinant prion protein into β-sheet rich fibrils
Mari Endo et al.
Journal of gastroenterology, 49(6), 1026-1039 (2013-07-13)
Daikenchuto (DKT), a gastrointestinal prokinetic Japanese herbal medicine, is prescribed for patients with postoperative ileus (POI) and adhesive bowel obstruction following abdominal surgery. Several mechanisms for the amelioration of POI by DKT have been suggested; however, it has remained unclear
S Srinivasa et al.
The British journal of surgery, 100(1), 66-74 (2012-11-08)
Goal-directed fluid therapy (GDFT) has been compared with liberal fluid administration in non-optimized perioperative settings. It is not known whether GDFT is of value within an enhanced recovery protocol incorporating fluid restriction. This study evaluated GDFT under these circumstances in

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