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Merck
CN

49782

Glycerol solution

puriss. p.a., 86-89% (T)

Synonym(s):

1,2,3-Propanetriol

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About This Item

Linear Formula:
HOCH2CH(OH)CH2OH · aq
CAS Number:
56-81-5
Molecular Weight:
92.09 (anhydrous basis)
UNSPSC Code:
50161901
NACRES:
NA.21
PubChem Substance ID:
329757526
EC Number:
200-289-5
Beilstein/REAXYS Number:
635685
MDL number:
MFCD00004722
Assay:
86-89% (T)
Bp:
182 °C/20 mmHg (lit.)
Vapor pressure:
<1 mmHg

Key Documents

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Product Name

Glycerol solution, puriss. p.a., 86-89% (T)

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

SMILES string

OCC(O)CO

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg

grade

puriss. p.a.

assay

86-89% (T)

form

viscous liquid

expl. lim.

2.6-11.3 %

impurities

≤0.001% aldehydes (as formaldehyde)
≤0.002% free acid (as CH3COOH)
≤0.05% fatty acid esters (as glycerol tributyrate)
11-14% water

ign. residue

≤0.01% (as SO4)

refractive index

n20/D 1.454

pH

5.5-8

bp

182 °C/20 mmHg (lit.)

density

1.252 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤2 mg/kg
sulfate (SO42-): ≤5 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Mg: ≤5 mg/kg
Mn: ≤1 mg/kg
NH4+: ≤5 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Zn: ≤1 mg/kg

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Application

Glycerol may be used in the synthesis of poly(glycerol sebacate) (PGS) pre-polymer, which is required for the fabrication of PGS scaffolds. It may be employed to protect the human red blood-cells from damage during the process of freezing and thawing.

General description

Glycerol is widely used in industries based on food, polymer, resins, tobacco, detergents, explosives, drugs and personal care products. It is most commonly employed cheap feedstock in the chemical industry. Its transformation to various commercial value-added chemicals has been proposed. A fast enzymatic assay for the determination of glycerol based on its reaction with ATP has been described.

wgk

WGK 1

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH3930
BCCF2925
BCCD2536
BCCB1995
BCBX5377

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A rapid enzymatic assay for glycerol.
Garland PB and Randle PJ.
Nature, 196, 987 - 988 (1962)
The mechanism of the protective action of glycerol against haemolysis by freezing and thawing.
J E LOVELOCK
Biochimica et biophysica acta, 11(1), 28-36 (1953-05-01)
Nafiseh Masoumi et al.
Journal of biomedical materials research. Part A, 101(1), 104-114 (2012-07-25)
Microfabricated poly(glycerol sebacate) (PGS) scaffolds may be applicable to tissue engineering heart valve leaflets by virtue of their controllable microstructure, stiffness, and elasticity. In this study, PGS scaffolds were computationally designed and microfabricated by laser ablation to match the anisotropy
Mario Pagliaro et al.
Angewandte Chemie (International ed. in English), 46(24), 4434-4440 (2007-05-02)
Today, industrial plants that produce glycerol are closing down and others are opening that use glycerol as a raw material, owing to the large surplus of glycerol formed as a by-product during the production of biodiesel. Research efforts to find
Shelley L Forrest et al.
The Journal of comparative neurology, 522(17), 3900-3927 (2014-07-22)
Artemin is a member of the glial cell line-derived neurotrophic factor (GDNF) family that has been strongly implicated in development and regeneration of autonomic nerves and modulation of nociception. Whereas other members of this family (GDNF and neurturin) primarily target
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