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D5879

Dimethyl sulfoxide

Name: Dimethyl sulfoxide
Brand: SIGALD

ReagentPlus^®, ≥99.5%

Synonym(s):

DMSO

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About This Item

Linear Formula:

(CH₃)₂SO

CAS Number:

67-68-5

Molecular Weight:

78.13

UNSPSC Code:

12191502

NACRES:

NA.21

PubChem Substance ID:

329798814

EC Number:

200-664-3

Beilstein/REAXYS Number:

506008

MDL number:

MFCD00002089

Assay:

≥99.5%

Technique(s):

immunoblotting: suitable

Bp:

189 °C (lit.)

Vapor pressure:

0.42 mmHg ( 20 °C)

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vapor density

2.7 (vs air)

Quality Level

200

vapor pressure

0.42 mmHg ( 20 °C)

product line

ReagentPlus^®

assay

≥99.5%

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

immunoblotting: suitable

impurities

≤0.1% water (Karl Fischer)

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubility

H₂O: soluble(lit.), acetone: soluble(lit.), benzene: soluble(lit.), chloroform: soluble(lit.), ethanol: soluble(lit.)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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Related Categories

Analytical Chromatography

Lab Chemicals

Solvents

General description

Dimethyl sulfoxide is an amphipathic molecule, soluble in both aqueous and organic solvents. It is commonly used as an aprotic solvent and also as a reagent in organic synthesis.

Application

DMSO has been used as a medium to prepare a chemiluminescence reagent that can be a substitute to commercially-available enhanced chemiluminescence kits for use in immunoblotting technique.

Biochem/physiol Actions

DMSO is a highly polar substance that can be used as an industrial solvent for organic and inorganic chemicals. It is also used as a protectant during cold storage of living cells. It is also useful for the oxidation of thiols and disulfides to sulfonic acids.

Packaging

Note: D5879-1L in plastic jerricans

Other Notes

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

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Lowe, O.G

The Journal of Organic Chemistry, 41 (1976)

Effects of cooling and equilibration in DMSO, and cryopreservation of mouse oocytes, on the rates of in vitro fertilization, development, and chromosomal abnormalities.

M Bouquet et al.

Molecular reproduction and development, 40(1), 110-115 (1995-01-01)

In a previous study, we have shown that the cryopreservation of mouse oocytes caused increases in the rates of degeneration and of digynic polyploid embryos, while the fertility of frozen-thawed oocytes was decreased. In this study, we have attempted to

Effect of dimethyl sulfoxide (DMSO) on cryopreservation of porcine mesenchymal stem cells (pMSCs).

Sun-A Ock et al.

Cell transplantation, 20(8), 1231-1239 (2011-02-08)

Dimethyl sulfoxide (DMSO), a commonly used cryoprotectant in cryopreservation procedures, is detrimental to viability of cells. In this view point, a comparative study was carried out to evaluate the effect of DMSO on porcine mesenchymal stem cells (pMSCs). We compared

Factors regulating the timing of puberty onset in female rhesus monkeys (Macaca mulatta): role of prenatal androgens, social rank, and adolescent body weight.

Julia L Zehr et al.

Biology of reproduction, 72(5), 1087-1094 (2004-12-31)

This study investigated whether prenatal androgen exposure, social rank, and body weight are factors regulating pubertal development in outdoor-housed female rhesus monkeys. Subjects' mothers received injections of testosterone enanthate (20 mg/ wk), flutamide (an androgen receptor blocker, 30 mg/kg twice

Vitrification of human embryos subjected to blastomere biopsy for pre-implantation genetic screening produces higher survival and pregnancy rates than slow freezing.

Levent Keskintepe et al.

Journal of assisted reproduction and genetics, 26(11-12), 629-635 (2009-12-08)

Cryopreservation of blastocysts, especially those subjected to the trauma due to blastomere biopsy for the purposes of pre-implantation genetic screening (PGS), requires significant optimization. Laboratory and clinical outcomes were compared to determine the effect of two different cryopreservation techniques on

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Global Trade Item Number

SKU	GTIN
D5879-10L	04061837717116
D5879-2.5L	04061833586969
D5879-5L	04061837227219
D5879-500ML	04061837227196
D5879-6X1L	04061837227226
D5879-100ML	04061837227158
D5879-1L	04061837227165
D5879-4L	04061833586976

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