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M7506

Sigma-Aldrich

Magnesium sulfate

anhydrous, ReagentPlus®, ≥99.5%

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Empirical Formula (Hill Notation):
MgSO4
CAS Number:
7487-88-9
Molecular Weight:
120.37
EC Number:
231-298-2
MDL number:
MFCD00011110
PubChem Substance ID:
329817908
NACRES:
NA.21

grade

anhydrous

Quality Level

200

Agency

suitable for SM 5210

vapor density

<0.01 (vs air)

vapor pressure

<0.1 mmHg ( 20 °C)

product line

ReagentPlus®

Assay

≥99.5%

form

powder

pH

~7.9 (25 °C, 50 g/L)

SMILES string

[Mg++].[O-]S([O-])(=O)=O

InChI

1S/Mg.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2

InChI key

CSNNHWWHGAXBCP-UHFFFAOYSA-L

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General description

Magnesium sulfate is a magnesium salt with tocolytic ability. Its role to induce an analgesic effect during intraoperative and postoperative periods has been investigated. It is reported to prevent eclampsia. Its ability to remove water from water-miscible solvents by salting-out phase separation has been studied.

Application

Magnesium sulfate (anhydrous) can be used as a catalyst:      
  • In Biginelli reactions to synthesize dihydropyrimidinones by solvent-free conditions.      
  • In the synthesis of 2-imidazolines by the reaction of aldehydes and ethylenediamine in the presence of hydrogen peroxide and sodium iodide.

The mixture of MgSO4 and bayerite is used to prepare single-phase,MgAl2O4 spinel nanoparticles by calcining the powder mixture at 800 oC.
MgSO4 (anhydrous) can also be used as a drying agent in organic synthesis for the removal of traces of water from organic extracts.
Magnesium sulfate may be used as a drying agent for organic extracts.

Other Notes

Go to Redi-Dri™ Product Listing 746452

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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A facile and efficient synthesis of 2-imidazolines from aldehydes using hydrogen peroxide and substoichiometric sodium iodide
Bai Guo-yi, et al.
Synthesis, 2011(10), 1599-1603 (2011)
Anhydrous magnesium sulfate mediated solvent-free synthesis of dihydropyrimidin-2 (1H)-ones at ambient temperature
Pore DM, et al.
Australian Journal of Chemistry, 60(6), 435-438 (2007)
Synthesis of MgAl2O4 spinel nanoparticles using a mixture of bayerite and magnesium sulfate
Su Xinghua, et al.
Journal of Nanoparticle Research, 12(5), 1813-1819 (2010)
J P Elliott
American journal of obstetrics and gynecology, 147(3), 277-284 (1983-10-01)
Magnesium sulfate (MgSO4) has been successfully used to inhibit premature labor. A retrospective review was performed on the use of MgSO4 as a tocolytic agent at Memorial Hospital, Long Beach, California, during a 4-year period (1978-1982). Three hundred fifty-five patients
H Koinig et al.
Anesthesia and analgesia, 87(1), 206-210 (1998-07-14)
In a randomized, double-blind study with two parallel groups, we assessed the analgesic effect of perioperative magnesium sulfate administration in 46 ASA physical status I or II patients undergoing arthroscopic knee surgery with total i.v. anesthesia. The patients received either
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Chromatograms

suitable for GC/MS

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