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P1386

Sigma-Aldrich

Propionic acid

≥99.5%

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Synonym(s):
Acid C3, Propanoic acid, Propanyl acid
Linear Formula:
CH3CH2COOH
CAS Number:
79-09-4
Molecular Weight:
74.08
Beilstein:
506071
EC Number:
201-176-3
MDL number:
MFCD00002756
eCl@ss:
39021305
PubChem Substance ID:
329820094
NACRES:
NA.21

vapor density

2.55 (vs air)

Quality Level

200

vapor pressure

2.4 mmHg ( 20 °C)

Assay

≥99.5%

autoignition temp.

955 °F

expl. lim.

12.1 %

impurities

≤0.25% water (Karl Fischer)

color

≤10, APHA:

refractive index

n20/D 1.386 (lit.)

bp

141 °C (lit.)

mp

−24-−23 °C (lit.)

density

0.993 g/mL at 25 °C (lit.)

SMILES string

CCC(O)=O

InChI

1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)

InChI key

XBDQKXXYIPTUBI-UHFFFAOYSA-N

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General description

Propionic acid (PA) is a naturally occurring carboxylic acid, which in its pure state exists as a colorless corrosive liquid with an unpleasant odor. It is miscible in water. Industrially it is produced by hydrocarboxylation of ethylene in presence nickel carbonyl as a catalyst. PA has been found to reduce food intake, lower the fatty acids content in plasma and liver, might improve tissue insulin sensitivity and exerts immunosuppressive actions. Propionic acid is an excellent raw material as it is stable, cheap and safe and can even be used as a food additive.

Signal Word

Danger

Hazard Statements

H226 - H314 - H335

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

129.2 °F - closed cup

Flash Point(C)

54 °C - closed cup

Regulatory Information

危险化学品

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Kaori Watanabe et al.
Cell reports, 28(10), 2594-2607 (2019-09-05)
During evolution, organisms have acquired variable feeding habits. Some species are nutritional generalists that adapt to various food resources, while others are specialists, feeding on specific resources. However, much remains to be discovered about how generalists adapt to diversified diets.
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The evolution of embryological development has long been characterized by deep conservation. In animal development, the phylotypic stage in mid-embryogenesis is more conserved than either early or late stages among species within the same phylum. Hypotheses to explain this hourglass
Maria Litovchenko et al.
Science advances, 7(5) (2021-01-31)
Natural genetic variation affects circadian rhythms across the evolutionary tree, but the underlying molecular mechanisms are poorly understood. We investigated population-level, molecular circadian clock variation by generating >700 tissue-specific transcriptomes of Drosophila melanogaster (w1118 ) and 141 Drosophila Genetic Reference
Flour and Breads and their Fortification in Health and Disease Prevention.
Victor R. Preedy, Ronald Ross Watson, Vinood B
Technology & Engineering, 476-476 (2011)
Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
Sa'ad, H., et al.
Molecular and Cellular Biology, 1801 (11), 1175-1183 (2010)
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