Key Documents

View All Documentation

01640

Acridine

Name: Acridine
Brand: SIGMA

BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₃H₉N

CAS Number:

260-94-6

Molecular Weight:

179.22

PubChem Substance ID:

329747337

eCl@ss:

39210107

UNSPSC Code:

12171500

NACRES:

NA.32

EC Number:

205-971-6

MDL number:

MFCD00005025

Beilstein/REAXYS Number:

120200

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

product line

BioReagent

Quality Level

100

assay

≥97.0% (HPLC)

bp

346 °C (lit.)

mp

106-111 °C, 107-110 °C (lit.)

solubility

ethanol: 0.5 g/10 mL, clear (hot), carbon disulfide: soluble, diethyl ether: soluble, ethanol: soluble, hydrocarbons: soluble

fluorescence

λ_ex 360 nm; λ_em 417 nm in ethanol

suitability

suitable for fluorescence

SMILES string

c1ccc2nc3ccccc3cc2c1

InChI

1S/C13H9N/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12/h1-9H

InChI key

DZBUGLKDJFMEHC-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

The fluorescence intensity, fluorescence quantum yield, time of decay, and lifetime are dependent upon the solvent. For example, the fluorescence intensity varies from being moderately strong in aqueous solution and very weak in hydrocarbon solvents. Additionally, the quantum yield has been demonstrated to increase with decreasing temperatures, for all solvent conditions.

Analysis Note

In addition to the emission maximum at 417 nm, there are lower maxima at 435, 400 and 460 nm.

pictograms

GHS07,GHS09

signalword

Warning

hcodes

H302,H315,H319,H335,H410

pcodes

P261 - P264 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Subnanosecond Time-Resolved Fluorescence of Acridine in Solution

Diverdi, L. A., and Topp, M. R.

The Journal of Physical Chemistry, 88, 3447-3447 (1984)

Functional opsonic activity of human serum antibodies to inner core lipopolysaccharide (galE) of serogroup B meningococci measured by flow cytometry.

J S Plested et al.

Infection and immunity, 69(5), 3203-3213 (2001-04-09)

A recently described flow cytometric opsonophagocytic assay (OPA) was adapted to quantify the functional activity of serum antibodies specifically directed against serogroup B inner core lipopolysaccharide (LPS) of Neisseria meningitidis. The percentage of human peripheral polymorphonuclear leukocytes and monocytes (PMNms)

Broad adaptive immune responses to M. tuberculosis antigens precede TST conversion in tuberculosis exposed household contacts in a TB-endemic setting.

Ulrike K Buchwald et al.

PloS one, 9(12), e116268-e116268 (2014-12-31)

The identification of Mycobacterium-tuberculosis (Mtb) infected individuals remains a challenge due to an insufficient understanding of immune responses detected with the current diagnostic tests for latent tuberculosis i.e. the tuberculin skin test (TST) or IFN-γ release assays (IGRAs) and an

Protein tyrosine phosphatase PTP-RR regulates corticosteroid sensitivity.

Yoshiki Kobayashi et al.

Respiratory research, 17, 30-30 (2016-03-26)

We have recently reported that protein phosphate 2A (PP2A) inactivation resulted in increased phosphorylation of the mitogen-activated protein kinase (MAPK) c-Jun N-terminal kinase 1 (JNK1) and glucocorticoid receptors (GR) at Ser(226), thereby reducing GR nuclear translocation and causing corticosteroid insensitivity

Natural resistance to intracellular infections: natural resistance-associated macrophage protein 1 (Nramp1) functions as a pH-dependent manganese transporter at the phagosomal membrane.

N Jabado et al.

The Journal of experimental medicine, 192(9), 1237-1248 (2000-11-09)

Mutations at the natural resistance-associated macrophage protein 1 (Nramp1) locus cause susceptibility to infection with antigenically unrelated intracellular pathogens. Nramp1 codes for an integral membrane protein expressed in the lysosomal compartment of macrophages, and is recruited to the membrane of

View All Related Papers

Global Trade Item Number

SKU	GTIN
T21105-50G	04061831836981
T21105-10G	04061831827545
01640-10G	04061838609540
01640-1G	04061826678374
01640-50G	04061838609557

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service