01930
Adenosine 5′-monophosphate disodium salt
≥99.0% (HPLC)
Synonym(s):
5′-AMPdisodium salt,, Adenylic acid disodium salt, 5′-AMP-Na2
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About This Item
Empirical Formula (Hill Notation):
C10H12N5Na2O7P
CAS Number:
Molecular Weight:
391.18
PubChem Substance ID:
eCl@ss:
32160414
UNSPSC Code:
41106305
NACRES:
NA.51
EC Number:
224-961-2
MDL number:
Beilstein/REAXYS Number:
3586732
Assay:
≥99.0% (HPLC)
Biological source:
microbial (Candida utilis), synthetic
Form:
powder
Quality Segment
biological source
microbial (Candida utilis), synthetic
assay
≥99.0% (HPLC)
form
powder
optical activity
[α]20/D −43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)
impurities
≤26% water
SMILES string
[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O
InChI
1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
InChI key
QGXLVXZRPRRCRP-IDIVVRGQSA-L
Application
Adenosine 5′-monophosphate (5′-AMP) has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). It may be used as a substrate by a variety of enzymes such as AMP-thymidine kinase (EC 2.7.1.114), AMP deaminase (EC 3.5.4.6) and 5′-nucleotidase (EC 3.1.3.5).
Adenosine 5′-monophosphate disodium salt has been used:
- as a dissolved organic phosphorus (DOP) compound to study its rate of hydrolysis in Escherichia coli lysates
- to induce calcium responses in Fura2-loaded osteoblast (C2-OB)
- as a nucleotide metabolite in the medium for the isolation, culture, and identification of glioma stem cells (GSCs)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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