Skip to Content
Merck
CN

05130

L-Alanine

≥99.0% (NT)

Synonym(s):

(S)-2-Aminopropionic acid, L-α-Aminopropionic acid

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C3H7NO2
CAS Number:
56-41-7
Molecular Weight:
89.09
NACRES:
NA.26
PubChem Substance ID:
329747640
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-273-8
MDL number:
MFCD00064410
Beilstein/REAXYS Number:
1720248

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

QNAYBMKLOCPYGJ-REOHCLBHSA-N

InChI

1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1

assay

≥99.0% (NT)

form

powder or crystals

optical activity

[α]20/D +14.0±1°, c = 5% in 5 M HCl

impurities

≤0.3% foreign amino acids

ign. residue

≤0.1% (as SO4)

loss

≤0.1% loss on drying, 110 °C

color

colorless to white

mp

314.5 °C

solubility

H2O: soluble 89.1 g/l at 20 degrees c, diethyl ether: insoluble, ethanol: soluble (cold 80%)

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, NH4+: ≤100 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

application(s)

detection
peptide synthesis

Quality Level

200

Looking for similar products? Visit Product Comparison Guide

Application

L-Alanine is used as a standard to determine absolute concentration of a protein within a mixture of other proteins measured with SI traceability.

Biochem/physiol Actions

Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions. The amino group of glutamate is transferred to pyruvate via alanine aminotransferase, forming alanine and α-ketoglutarate. The alanine is passed into the blood and transported to the liver. This reaction is reversed in the liver where pyruvate can be used in gluconeogenesis to form glucose, which may return to other tissues through the circulatory system. Increased alanine levels correlate with higher blood pressure, energy intake, cholesterol levels, and body mass index.
L-alanine has the ability to promote the expression of ferritin and antioxidant stress proteins, heme oxygenase-1 (HO-1).

Preparation Note

L-Alanine completely dissolves in water at a concentration of 89.1 g/l at 20°C to yield solution. It is also soluble in 80% ethanol and insoluble in ether.

Other Notes

Preparation of 2-chloropropionic acid; Reduction of derivatives to the aldehyde

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN6914
BCCM6763
BCCM2801
BCCM1520
BCCM1174

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

H. Kogen et al.
Journal of the Chemical Society. Chemical Communications, 311-311 (1987)
B. Koppenhoefer et al.
Synthesis, 316-316 (1982)
M. Narita et al.
Tetrahedron Letters, 23, 525-525 (1982)
K. Watanabe et al.
Synthesis, 225-225 (1987)
Nina Grosser et al.
Biochemical and biophysical research communications, 314(2), 351-355 (2004-01-22)
The amino acid L-alanine has been shown to exert long-term cytoprotection by as yet unidentified molecular mechanisms. Using cultured human endothelial cells (ECV 304), the present study investigates the effect of L-alanine on hydrogen peroxide-mediated cytotoxicity and expression of the
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service