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Merck
CN

06855

Sigma-Aldrich

Kollisolv® PEG E 400

greener alternative

Synonym(s):

Poly(ethylene glycol), Lutrol E 400, Macrogol 400, Polyethylene glycol, Polyethylene glycol 400, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12161900
NACRES:
NA.25

Key Documents

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form

liquid

Quality Level

100

mol wt

average Mw 380-420 g/mol (from OH-value (56100*2/OHZ))

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

electrophoresis: suitable

impurities

reducing substances, complies
≤0.1% sulfated ash
≤0.25% ethylene glycol and diethylene glycol (sum)
≤0.5 g acetic acid (per 100 g)
≤1 ppm ethylene oxide
≤1 ppm lead (verified on random samples only)
≤1.0% water
≤10 ppm dioxan
≤15 ppm formaldehyde
≤5 ppm heavy metals (verfied on random samples only)
≤620 ppm ethylene glycol

pH

4.5-7.0 (50 g/L)

viscosity

105-130 mPa.s(20 °C) (6.8-8.0 CS (98.9°C)

hydroxyl value

267‑295 mg KOH/g

solubility

H2O: 10%, clear, colorless

suitability

complies for acidity or alkalinity

greener alternative category

Aligned

SMILES string

C(CO)O
C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Kollisolv polyethylene glycols are used as thickening agents and gel binders in the pharmaceutical industry.
This research grade product is intended for use in R&D and development only.

Other Notes

The PEG E grades of Kollisolv are polyethylene glycols (macrogols) of different molecular weights.

Legal Information

Kollisolv is a registered trademark of BASF

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN8383
BCCN5138
BCCN0025
BCCL8493
BCCL3459

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D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a

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