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Merck
CN

08075

Potassium β-hydroxypyruvate

≥95.0% (NT)

Synonym(s):

β-Hydroxypyruvic acid potassium salt, 3-Hydroxy-2-oxopropionic acid potassium salt

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About This Item

Linear Formula:
HOCH2COCOOK
CAS Number:
Molecular Weight:
142.15
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
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assay

≥95.0% (NT)

form

powder

SMILES string

[K+].OCC(=O)C([O-])=O

InChI

1S/C3H4O4.K/c4-1-2(5)3(6)7;/h4H,1H2,(H,6,7);/q;+1/p-1

InChI key

GQHLMYFYRZSQRJ-UHFFFAOYSA-M

Biochem/physiol Actions

Hydroxypyruvate is a metabolite involved in the pathway of carbon in photorespiration.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Edward G Hibbert et al.
Journal of biotechnology, 131(4), 425-432 (2007-09-11)
We have used active-site targeted directed evolution by saturation mutagenesis to improve the activity of E. coli transketolase towards non-phosphorylated substrates. Residues were selected for each set based on either structural proximity to substrate, or on phylogenetic variation. Each library
Stefan Timm et al.
Plant physiology, 155(2), 694-705 (2011-01-06)
Hydroxypyruvate (HP) is an intermediate of the photorespiratory pathway that originates in the oxygenase activity of the key enzyme of photosynthetic CO(2) assimilation, Rubisco. In course of this high-throughput pathway, a peroxisomal transamination reaction converts serine to HP, most of
C V Givan et al.
Plant physiology, 100(2), 552-556 (1992-10-01)
Glyoxylate and hydroxypyruvate are metabolites involved in the pathway of carbon in photorespiration. The chief glyoxylate-reducing enzyme in leaves is now known to be a cytosolic glyoxylate reductase that uses NADPH as the preferred cofactor but can also use NADH.
Stefan Timm et al.
The Plant cell, 20(10), 2848-2859 (2008-10-28)
Deletion of any of the core enzymes of the photorespiratory cycle, one of the major pathways of plant primary metabolism, results in severe air-sensitivity of the respective mutants. The peroxisomal enzyme hydroxypyruvate reductase (HPR1) represents the only exception to this
Kai Yang et al.
Chemico-biological interactions, 191(1-3), 315-321 (2011-03-08)
Previously, we showed that dietary fructose or its carbonyl metabolites, glyceraldehyde and glycolaldehyde, could be oxidized by inflammatory reactive oxygen species (ROS), products of immune cells, to form highly toxic and genotoxic products, such as glyoxal. Glycolaldehyde-caused hepatocyte protein carbonylation

Global Trade Item Number

SKUGTIN
A9502-100MG04061832883397
1012531-200MG04061833839065
A9502-1G04061826752210
08075-1G-F04061826680162
08075-250MG-F04061832860008

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