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Merck
CN

08114

Magnesium L-pidolate

98.0-102.0% (calc. on dry substance, T)

Synonym(s):

MAG2, Magnesium (S)-2-pyrrolidone-5-carboxylate, Magnesium 5-oxo-L-proline

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About This Item

Empirical Formula (Hill Notation):
C10H12N2MgO6
CAS Number:
Molecular Weight:
280.52
PubChem Substance ID:
UNSPSC Code:
12352204
NACRES:
NA.25
EC Number:
263-365-7
MDL number:
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Quality Level

assay

98.0-102.0% (calc. on dry substance, T)

optical activity

[α]/D -24±1.5°, c = 0.5 in H2O

pH

5.5-7.5 (25 °C, 50 mg/mL in H2O)

solubility

H2O: 50 mg/mL, clear, colorless

anion traces

chloride (Cl-): ≤500 mg/kg, nitrate (NO3-): ≤50 mg/kg, phosphate (PO43-): ≤50 mg/kg, sulfate (SO42-): ≤200 mg/kg

cation traces

Ag: ≤5 mg/kg, Al: ≤5 mg/kg, As: ≤0.5 mg/kg, Ba: ≤5 mg/kg, Be: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤50 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤10 mg/kg, Li: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Ti: ≤5 mg/kg, Zn: ≤5 mg/kg, Zr: ≤5 mg/kg

InChI

1S/2C5H7NO3.Mg/c2*7-4-2-1-3(6-4)5(8)9;/h2*3H,1-2H2,(H,6,7)(H,8,9);/q;;+2/p-2/t2*3-;/m00./s1

InChI key

JQAACYUZYRBHGG-QHTZZOMLSA-L

Application

Magnesium L-pidolate, or MAG2, has been used in a study to inform radiopharmaceuticals for diagnostic imaging of breast cancer. MAG2 has also been used in a study to assess the influence of the bifunctional chelate on the biological behavior of 99mtc-labeled chemotactic peptide conjugates. MAG2 has also been used in a study to learn more about the antimicrobial peptides from the skin secretions of amphibians.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Anti-MUC1 aptamers: radiolabelling with 99mTc and biodistribution in MCF-7 tumour-bearing mice
Da Pieve, C., et al.
Nuclear Medicine and Biology, 36, 702-710 (2009)
Nicholas C Smith et al.
International journal for parasitology, 51(2-3), 95-121 (2020-12-22)
Toxoplasmosis is caused by Toxoplasma gondii, an apicomplexan parasite that is able to infect any nucleated cell in any warm-blooded animal. Toxoplasma gondii infects around 2 billion people and, whilst only a small percentage of infected people will suffer serious
K Verbeke et al.
Nuclear medicine and biology, 27(8), 769-779 (2001-01-11)
Conjugates of For-MLFK and For-NleLFNleYK with S-benzyl mercaptoacetyl dipeptides containing, respectively, zero, one, and two carboxyl functions in their structures were prepared and labeled with (99m)Tc. In vitro binding studies using isolated human granulocytes indicated specific receptor binding of the



Global Trade Item Number

SKUGTIN
D58600-25G04061833586921
D58600-5G04061836824686
08114-500G04061838652119