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About This Item
Empirical Formula (Hill Notation):
C12H11NO4
CAS Number:
Molecular Weight:
233.22
Beilstein:
7927205
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.32
product line
BioReagent
Quality Level
Assay
~90% (HPLC)
form
powder
solubility
DMF: soluble
DMSO: soluble
aqueous base: soluble
fluorescence
λex 350 nm; λem 433 nm in methanol
suitability
suitable for fluorescence
SMILES string
CC1=C(CC(O)=O)C(=O)Oc2cc(N)ccc12
CC1=C(CC(O)=O)C(=O)Oc2cc(N)ccc12
InChI
1S/C12H11NO4/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4H,5,13H2,1H3,(H,14,15)
InChI key
QEQDLKUMPUDNPG-UHFFFAOYSA-N
Related Categories
Application
AMCA is a useful agent for labeling proteins. Demonstrates a characteristic absorption peak at 345 nm with a fluorescence emission at 440-460 nm (blue region); however, when conjugated with proteins the absorption peak shifts to 355 nm with a fluorescence emission at 440-460 nm. It has a high fluorescence yield with a sufficient Stokes shift (100 nm) and is relatively photostable . Relatively easy to activate and couple to the N-terminal amino group of a peptide resulting in an acid stable amide bond .
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Useful blue fluorophore for immunofluorescence, λabs ~350 nm, λem ~440 nm
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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