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103R-9

CD3 (MRQ-39) Rabbit Monoclonal Antibody

Name: CD3 (MRQ-39) Rabbit Monoclonal Antibody
Brand: SIGMA

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

MRQ-39, monoclonal

Application:

IHC (p)

Citations:

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biological source

rabbit

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

MRQ-39, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

pkg of 0.1 mL concentrate (103r-94), pkg of 0.5 mL concentrate (103R-95), pkg of 1.0 mL concentrate (103R-96), pkg of 1.0 mL predilute (103R-97), pkg of 7.0 mL predilute (103R-98)

manufacturer/tradename

Cell Marque^®

IVD

for in vitro diagnostic use

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

isotype

IgG1

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... CD3E(916)

Related Categories

Cell Marque

Cell Marque™ Primary Antibodies

Clinical & Diagnostics

General description

Anti-CD3 has been considered the best all around T-cell marker. This antibody reacts with an antigen present in early thymocytes. The positive staining of this marker may represent a sign of early commitment to the T-Cell lineage.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

RUO

Other Notes

CD3 Positive Control Slides, Product No. 103S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Regulatory Information

监管及禁止进口产品

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Leukocyte cell surface enzymology: CD45 (LCA, T200) is a protein tyrosine phosphatase.

E A Clark et al.

Immunology today, 10(7), 225-228 (1989-07-01)

During 1987, striking advances were made in defining the receptors and ligands for cell-to-cell adhesion interactions involving leukocytes. In 1988, two major leukocyte differentiation antigens, CD10 (cALLA) and CD45 (LCA, T200), were shown to be enzymes while two other markers

SM Denning, et al.

Leucocyte Typing III, 144-147 (1987)

Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody.

P C Beverley et al.

European journal of immunology, 11(4), 329-334 (1981-04-01)

The properties of human lymphocyte fractions isolated either by sheep red cell(E) rosetting or by fluorescence-activated cell sorting after staining with UCHT1 monoclonal anti-T cell antibody have been compared. Two populations of E+ cells with very different phenotype and function

Micronodular T-cell/histiocyte-rich large B-cell lymphoma of the spleen: histology, immunophenotype, and differential diagnosis.

Ahmet Dogan et al.

The American journal of surgical pathology, 27(7), 903-911 (2003-06-27)

Occasionally, primary large B-cell lymphomas (LBLs) arising in the spleen present with a micronodular pattern involving the splenic white pulp but sparing the red pulp. Histologically, the nodules contain scattered large B cells in a background of numerous T cells

T-cell-rich B-cell lymphoma - diagnostic and therapeutic aspects.

Ulla Axdorph et al.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 110(5), 379-390 (2002-06-22)

Morphologically, T-cell-rich B-cell lymphoma (TCRB-NHL) may be indistinguishable from Hodgkin's disease (HD). Immunophenotyping may be helpful in the separation of these entities. TCRB-NHL is occasionally misdiagnosed and treated as HD. However, information is limited regarding clinical characteristics and outcome of

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Global Trade Item Number

SKU	GTIN
103R-95	0841683123163
103R-98	0841683123194
103R-97	0841683123187
103R-94	0841683123156
103R-96-RUO	04061836548919
103R-96	0841683123170

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