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138M-1

CD138/syndecan-1 (B-A38) Mouse Monoclonal Antibody

Name: CD138/syndecan-1 (B-A38) Mouse Monoclonal Antibody
Brand: SIGMA

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

B-A38, monoclonal

Application:

IHC (p)

Citations:

Technical Service

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biological source

mouse

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

B-A38, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (138M-14), vial of 0.5 mL concentrate (138M-15), bottle of 1.0 mL predilute (138M-17), vial of 1.0 mL concentrate (138M-16), bottle of 7.0 mL predilute (138M-18)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:200

isotype

IgG1

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... SDC1(6382)

Related Categories

Cell Marque

Cell Marque™ Primary Antibodies

Clinical & Diagnostics

General description

CD138, Syndecan 1, is a transmembrane heparan sulfate proteoglycan, present mainly in a variety of epithelial tissues, participating in cell proliferation, cell migration, intercellular communication, and cell-matrix interactions. In lymphoid tissues, CD138 is expressed in the late stages of B-cell differentiation with progression towards plasma cells. Anti-CD138 is a good marker to selectively identify plasma cells, benign or malignant, in lymphoid tissues CD138 is also expressed in a variety of epithelial cells.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

RUO

Other Notes

CD138/syndecan-1 Positive Control Slides, Product No. 138S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

0000474126

0000466478

0000460495

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Inflammation and cytokeratin 7/20 staining of cardiac mucosa in young patients with and without Helicobacter pylori infection.

A Oksanen et al.

Journal of clinical pathology, 58(4), 376-381 (2005-03-26)

Both Helicobacter pylori and gastro-oesophageal reflux disease (GORD) may cause inflammation in cardiac mucosa. Intestinal metaplasia (IM) is found more often in GORD associated inflammation than in inflammation caused by H pylori, especially in young individuals. To examine morphological differences

Said J, et al.

WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 261-261 null

Said J, et al.

WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 261-261 null

Syndecan-1 (CD138) expression in human non-Hodgkin lymphomas.

A Sebestyén et al.

British journal of haematology, 104(2), 412-419 (1999-03-02)

Syndecan-1, an important transmembrane heparan sulphate proteoglycan is expressed in distinct stages of differentiation of normal lymphoid cells: in pre-B cells and Ig-producing plasma cells; however, its normal function, or presence in lymphoid malignancies, is still largely unknown. The expression

CD138/syndecan-1: a useful immunohistochemical marker of normal and neoplastic plasma cells on routine trephine bone marrow biopsies.

M Chilosi et al.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 12(12), 1101-1106 (2000-01-05)

Detection of abnormal numbers and/or distribution of bone marrow (BM) plasma cells (PCs) on trephine biopsies can be important in the differential diagnosis of multiple myeloma (MM) and other PC disorders. A variety of immunohistochemical markers can potentially improve the

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Global Trade Item Number

SKU	GTIN
138M-16	0841683124764
138M-16-RUO	04061836567538
138M-14	0841683124733
138M-17	0841683104957
138M-18	0841683124771
138M-15	0841683124740

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