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Merck
CN

14202

Diisopropyl-fluorophosphatase

≥30 U/mg

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
Specific activity:
≥30 U/mg
Biological source:
fermentation/recombinant
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biological source

fermentation/recombinant

Quality Level

form

lyophilized solid

specific activity

≥30 U/mg

storage temp.

−20°C

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

One unit corresponds to the amount of enzyme which hydrolyzes 1 μmol diisopropyl fluorophosphate per minute at pH 8.1 and 22 °C


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

监管及禁止进口产品

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Marc-Michael Blum et al.
Biochemistry, 47(18), 5216-5224 (2008-04-10)
A wide range of toxic organophosphorus pesticides and nerve agents is effectively hydrolyzed by the structurally related phosphotriesterase enzymes paraoxonase (PON1) from human plasma and diisopropyl fluorophosphatase (DFPase) from the squid Loligo vulgaris. Both enzymes have potential use as medical
Jürgen Gäb et al.
Analytical and bioanalytical chemistry, 396(3), 1213-1221 (2009-11-28)
The enzyme diisopropyl fluorophosphatase (DFPase, EC 3.1.8.2) from the squid Loligo vulgaris effectively catalyzes the hydrolysis of diisopropyl fluorophosphate (DFP) and a number of organophosphorus nerve agents, including sarin, soman, cyclosarin, and tabun. Until now, determination of kinetic data has
Marc-Michael Blum et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(3), 713-718 (2009-01-13)
Hydrogen atoms constitute about half of all atoms in proteins and play a critical role in enzyme mechanisms and macromolecular and solvent structure. Hydrogen atom positions can readily be determined by neutron diffraction, and as such, neutron diffraction is an



Global Trade Item Number

SKUGTIN
14202-10MG04061833471661
14202-50MG04061833471678