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Merck
CN

14300

Betaine monohydrate

≥99.0% (NT)

Synonym(s):

1-carboxy-n,n,n-trimethylmethanaminium hydroxide, 2-(trimethylammonio)acetate hydrate, glycine betaine hydrate

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About This Item

Linear Formula:
(CH3)3N+CH2COO- · H2O
CAS Number:
Molecular Weight:
135.16
UNSPSC Code:
51171529
NACRES:
NA.25
PubChem Substance ID:
EC Number:
203-490-6
Beilstein/REAXYS Number:
3626258
MDL number:
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Quality Segment

assay

≥99.0% (NT)

form

solid

solubility

H2O: 0.1 g/mL, clear, colorless

storage temp.

2-8°C

SMILES string

O.C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2.H2O/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H2

InChI key

NJZRLXNBGZBREL-UHFFFAOYSA-N

Application

Betaine monohydrate:

  • is suitable for use to improve the PCR amplification of GC-rich DNA sequences by reducing the formation of secondary structure caused by GC-rich regions
  • is suitable for use as a component of PCR reaction mixture
  • is suitable for use in a study to identify yield enhancers of PCR
  • has been used to study nitrogen balance and nutrient digestibility in piglets fed diets deficient in methionine and low in compatible osmolytes
  • has also been used to compare the effects of pressure on three layered hydrates

Biochem/physiol Actions

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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