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14366C

EX-CELL® Advanced CHO Fed-batch Medium

liquid

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About This Item

NACRES:
NA.75
UNSPSC Code:
41161501
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sterility

sterile-filtered

Quality Level

500

product line

EX-CELL®

form

liquid

feature

subscription eligible

technique(s)

cell culture | mammalian: suitable (suspension)

components

L-glutamine: no

shipped in

ambient

storage temp.

2-8°C

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General description

EX-CELL® AdvancedCHO Fed-batch Medium is chemically-defined and contains no animal derived components. This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME). This medium is intended to be a part of a fed-batch platform, and used with EX-CELL® Advanced CHO Feed 1 (24367C - with glucose or 24368C - without glucose).

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Donot freeze. Protect from light. Several components of the medium arelight labile and should not be exposed to light for lengthy periods of time.

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

动植物来源培养基

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Certificates of Analysis (COA)

Lot/Batch Number
0000497763
0000497767
0000497767
0000497763
0000415524

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Weiyi Liu et al.
Biotechnology progress, 37(1), e3061-e3061 (2020-08-05)
Antibody-dependent cellular cytotoxicity (ADCC) is the primary mechanism of actions for several marketed therapeutic antibodies (mAbs) and for many more in clinical trials. The ADCC efficacy is highly dependent on the ability of therapeutic mAbs to recruit effector cells such

Articles

EX-CELL® Advanced™ CHO Fed-Batch System – Bioprocessing Technology Institute, Singapore Case Study

In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.

Low-Impurity Iron Sources: Case Studies in EX-CELL® Advanced Medium

Discover how low-impurity iron sources improve reliability and performance in recombinant protein production with EX-CELL® Advanced medium.

Upstream Bioprocessing Feed Strategies and Scalability: A Case Study with Cellvento® ModiFeed Prime COMP

This case study walks through optimizing feed and media for upstream bioprocessing and how it translates to large-scale bioreactors.

CHO Media and Feeds for Optimized Production of Therapeutic Proteins

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

See All

Related Content

Glycosylation Modulation in Fed-batch Production of Therapeutic Proteins

Enhance mAb and recombinant protein performance, efficacy, and stability with precise glycosylation modulation using the Cellvento® ModiFeed platform.

Cell Culture Media Development for mAbs

Learn more about cell culture media development for mAB development and manufacturing, and the products you need for this step.

Global Trade Item Number

SKUGTIN
14366C-10X1B04061838437426
14366C-5B04061838437464
14366C-100BD04061838437396
14366C-50B04061838438294
14366C-1000ML04061838821973
14366C-10B04061838437419
14366C-1B04061838385628
14366C-500BFS04061838437457
14366C-100BFS04061838437402
14366C-200BD04061838438270
14366C-2X5B04061838437440
14366C-20B04061838437433
14366C-200BFS04061838438287

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