Skip to Content
Merck
CN

14840

N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide

≥90% (HPLC)

Synonym(s):

Deoxy-BigCHAP, deoxy-BigCHAP

Sign In to View Organizational & Contract Pricing

Select a Size

About This Item

Empirical Formula (Hill Notation):
C42H75N3O15
CAS Number:
86303-23-3
Molecular Weight:
862.06
UNSPSC Code:
12161902
PubChem Substance ID:
57647220
NACRES:
NA.77

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

description

non-ionic

Assay

≥90% (HPLC)

mol wt

micellar average mol wt 10,500

aggregation number

8-16

impurities

≤4% water

CMC

1.1-1.4 mM (20-25°C)

storage temp.

2-8°C

SMILES string

O=C(N(CCCNC([C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)CCCNC([C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)CC[C@@H](C)[C@]1([H])[C@@]2(C)[C@@H](O)C[C@@]3([H])C([C@]2([H])CC1)CC[C@]4([H])C[C@H](O)CC[C@@]43C

InChI

1S/C42H75N3O15/c1-22(26-9-10-27-25-8-7-23-18-24(48)12-13-41(23,2)28(25)19-31(51)42(26,27)3)6-11-32(52)45(16-4-14-43-39(59)37(57)35(55)33(53)29(49)20-46)17-5-15-44-40(60)38(58)36(56)34(54)30(50)21-47/h22-31,33-38,46-51,53-58H,4-21H2,1-3H3,(H,43,59)(H,44,60)/t22-,23-,24-,25+,26-,27+,28+,29-,30-,31+,33-,34-,35+,36+,37-,38-,41+,42-/m1/s1

InChI key

OJSUWTDDXLCUFR-HGZMBBKESA-N

Application

N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide is used for membrane solubilisation and proteomic analysis.

Biochem/physiol Actions

N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide (deoxy-BigCHAP) is a non-ionic detergent that solubilizes cell membrane.

Preparation Note

N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide yields a clear, colorless solution in water at 50 mg/ml.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCK4679
BCCK1083
BCCK6054
BCCK0768
BCCC7762

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Y Akutsu et al.
Applied and environmental microbiology, 64(1), 62-67 (2005-12-14)
A polyester polyurethane (PUR)-degrading enzyme, PUR esterase, derived from Comamonas acidovorans TB-35, a bacterium that utilizes polyester PUR as the sole carbon source, was purified until it showed a single band in sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). This enzyme
The Use of Detergents to Purify Membrane Protein
Arnold T and Linke D
Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.], UNIT 4.8, doi: 10-doi: 10 (2008)
Individual dissolution of single-walled carbon nanotubes in aqueous solutions of steroid or sugar compounds and their Raman and near-IR spectral properties.
Ishibashi A, Nakashima N.
Chemistry (Easton), 12, 7595-7602 (2006)
A Aigner et al.
The Biochemical journal, 317 ( Pt 1), 213-218 (1996-07-01)
Microsomal cysteine-S-conjugate N-acetyltransferase catalyses the N-acetylation of various S-substituted cysteines in liver and kidney. We describe here the purification and more detailed characterization of this enzyme catalysing the final reaction of mercapturic acid biosynthesis, and thus playing a crucial role
L M Hjelmeland et al.
Analytical biochemistry, 130(2), 485-490 (1983-04-15)
Detergents containing either a cholic acid, a deoxycholic acid, or an octanoic acid-like hydrophobic moiety and a bisgluconamidopropyl polar group were synthesized. Extinction coefficients, partial specific volumes, critical micelle concentrations, and aggregation numbers were determined for each of the detergents.

Related Content

Detergents Properties and Applications

A guide displaying detergents' specifications and applications. The detergents are seperated into four groups (nonionic, anionic, cationic, zwitterionic) based on their hydrophillic head group. The guide also contains Non-Detergent Sulfobetaines.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service