168M-9
CD68 (Kp-1) Mouse Monoclonal Antibody
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
Kp-1, monoclonal
Application:
IHC (p)
Citations:
8
biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
Kp-1, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (168M-94), vial of 0.5 mL concentrate (168M-95), bottle of 1.0 mL predilute (168M-97), vial of 1.0 mL concentrate (168M-96), bottle of 7.0 mL predilute (168M-98)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG1κ
control
tonsil
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... CD68(968)
General description
Anti-CD68 marks cells of monocyte/macrophage lineage. This antibody is capable of staining monocytes, Kupffer cells, osteoclasts, granulocytes and their precursors; lymphomas are negative or show a few granules. This antibody may be useful for the identification of myelomonocytic and histiocytic tumors. Anti-CD68 may help to distinguish malignant fibrous histiocytoma from other pleomorphic sarcomas. However, since this detects a formalin-resistant epitope that may be associated with lysosomal granules, other lysosome-rich cells may also stain.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
CD68 Positive Control Slides, Product No. 168S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Regulatory Information
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J L Snow et al.
The British journal of dermatology, 133(1), 71-76 (1995-07-01)
The clinical, histopathological, and immunophenotypic characteristics of four cases of malignancy-associated multicentric reticulohistiocytosis (MMR) and one case each of diffuse cutaneous reticulohistiocytosis (DCR) and isolated reticulohistiocytoma (IR), are reviewed. In all four cases of MMR the cutaneous lesions and joint
L Martinez-Pomares et al.
Immunobiology, 195(4-5), 407-416 (1996-10-01)
Monoclonal antibodies directed against murine macrophage differentiation antigens provide tools to characterize novel glycoproteins, their expression by different macrophage subpopulations in situ and regulation by cytokines and other agents in vitro. Studies are in progress to determine ligands for these
L P Ruco et al.
American journal of clinical pathology, 92(3), 273-279 (1989-09-01)
The expression of macrophage antigens KP1, Mac, lysozyme, and alpha-1-antichymotrypsin was investigated on routine paraffin sections from 17 cases of Langerhans' cell histiocytosis (LCH). All the major clinical forms were represented, including single lesions and monosystemic and multisystemic disease. In
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 168M-96-RUO | 04061836539825 |
| 168M-96 | 0841683125358 |
| 168M-94 | 0841683125334 |
| 168M-95 | 0841683125341 |
| 168M-97 | 0841683125365 |
| 168M-98 | 0841683125372 |