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Merck
CN

17195

Fura 2 pentapotassium salt

suitable for fluorescence, ≥90% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C29H22K5N3O14
CAS Number:
Molecular Weight:
831.99
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
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Quality Level

assay

≥90% (HPLC)

form

solid

solubility

H2O: soluble

fluorescence

λex 355 nm; λem 495 nm in 0.1 M Tris pH 8.0, Ca2+

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

[K+].[K+].[K+].[K+].[K+].Cc1ccc(N(CC([O-])=O)CC([O-])=O)c(OCCOc2cc3cc(oc3cc2N(CC([O-])=O)CC([O-])=O)-c4ncc(o4)C([O-])=O)c1

InChI

1S/C29H27N3O14.5K/c1-15-2-3-17(31(11-24(33)34)12-25(35)36)20(6-15)43-4-5-44-21-7-16-8-22(28-30-10-23(46-28)29(41)42)45-19(16)9-18(21)32(13-26(37)38)14-27(39)40;;;;;/h2-3,6-10H,4-5,11-14H2,1H3,(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,41,42);;;;;/q;5*+1/p-5

InChI key

HQKWBBCTCLUGSX-UHFFFAOYSA-I

Other Notes

A very sensitive fluorescent calcium chelator that exhibits a spectral shift in excitation maxima on binding calcium


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。


Measurement of Ca2+ release in skinned fibers from skeletal muscle.
M Endo et al.
Methods in enzymology, 157, 12-26 (1988-01-01)
G Grynkiewicz et al.
The Journal of biological chemistry, 260(6), 3440-3450 (1985-03-25)
A new family of highly fluorescent indicators has been synthesized for biochemical studies of the physiological role of cytosolic free Ca2+. The compounds combine an 8-coordinate tetracarboxylate chelating site with stilbene chromophores. Incorporation of the ethylenic linkage of the stilbene



Global Trade Item Number

SKUGTIN
17195-1MG04061823353496