17927
9-Oxo-10(9H)-acridineacetic acid
derivatization grade (HPLC), ≥99.0% (T)
Synonym(s):
(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid, 10-(Carboxymethyl)-9(10H)acridone
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About This Item
Empirical Formula (Hill Notation):
C15H11NO3
CAS Number:
Molecular Weight:
253.25
UNSPSC Code:
12352106
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
227508
Assay:
≥99.0% (T)
Form:
solid
InChI
1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)
SMILES string
OC(=O)CN1c2ccccc2C(=O)c3ccccc13
InChI key
UOMKBIIXHQIERR-UHFFFAOYSA-N
grade
derivatization grade (HPLC)
assay
≥99.0% (T)
form
solid
mp
~289 °C (dec.)
Quality Level
Application
9-Oxo-10(9H)-acridineacetic acid and its analogs are used to study their potential activity as interferon inducers.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Induction of interferon in mice by sodium salt of 9-oxo-10-acridineacetic acid: specific enhancement by analogs.
Inglot AD, Mlochowski J, Szulc Z, et al.
Arch. Immunol. Ther. Exp., 33, 275-285 (1985)
A A Shul'diakov et al.
Eksperimental'naia i klinicheskaia farmakologiia, 75(11), 35-37 (2013-01-18)
The efficiency of cycloferon liniment in combined treatment of herpetic infection in patients with latent form of HIV infection has been assess by observations of 40 patients divided into two groups. In the first group, the standard treatment was supplemented
D S Sukhanov et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (1)(1), 65-69 (2013-06-29)
The results of pre-clinical research of cycloferon, remaxol and runihol on the model of experimental generalized tuberculosis, caused by the MBT with a different spectrum of drug sensitivity are presented. A considerable increase of the curative effect of the therapy
A A Shul'diakov et al.
Klinicheskaia meditsina, 90(8), 61-63 (2012-10-30)
The aim of the study was to estimate the efficacy of liniment cycloferon included in combined therapy of herpetic infection in 30 patients with psoriasis divided into 2 groups. Combined treatment of patients with recurrent herpetic infection promoted elimination of
E D Bazhanova
Eksperimental'naia i klinicheskaia farmakologiia, 75(7), 40-44 (2012-10-03)
In recent years, both interferons and inductors of endogenous interferon production find increasing use in clinical practice. The latter agents are characterized by high antiviral and immunomodulatory activity in the absence of serious side effects, which makes it possible to
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