17927
9-Oxo-10(9H)-acridineacetic acid
derivatization grade (HPLC), ≥99.0% (T)
Synonym(s):
(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid, 10-(Carboxymethyl)-9(10H)acridone
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About This Item
Empirical Formula (Hill Notation):
C15H11NO3
CAS Number:
Molecular Weight:
253.25
UNSPSC Code:
12352106
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
227508
Assay:
≥99.0% (T)
Form:
solid
InChI
1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)
SMILES string
OC(=O)CN1c2ccccc2C(=O)c3ccccc13
InChI key
UOMKBIIXHQIERR-UHFFFAOYSA-N
grade
derivatization grade (HPLC)
assay
≥99.0% (T)
form
solid
mp
~289 °C (dec.)
Quality Level
Application
9-Oxo-10(9H)-acridineacetic acid and its analogs are used to study their potential activity as interferon inducers.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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E D Bazhanova
Eksperimental'naia i klinicheskaia farmakologiia, 75(7), 40-44 (2012-10-03)
In recent years, both interferons and inductors of endogenous interferon production find increasing use in clinical practice. The latter agents are characterized by high antiviral and immunomodulatory activity in the absence of serious side effects, which makes it possible to
A A Shul'diakov et al.
Klinicheskaia meditsina, 90(8), 61-63 (2012-10-30)
The aim of the study was to estimate the efficacy of liniment cycloferon included in combined therapy of herpetic infection in 30 patients with psoriasis divided into 2 groups. Combined treatment of patients with recurrent herpetic infection promoted elimination of
Induction of interferon in mice by sodium salt of 9-oxo-10-acridineacetic acid: specific enhancement by analogs.
Inglot AD, Mlochowski J, Szulc Z, et al.
Arch. Immunol. Ther. Exp., 33, 275-285 (1985)
D S Sukhanov et al.
Eksperimental'naia i klinicheskaia farmakologiia, 75(9), 32-36 (2012-11-20)
The results of an experimental study of the efficiency of cycloferon included in a complex chemotherapy of generalized drug-resistant mycobacterium tuberculosis (MBT) are presented. It is established that cycloferon (3.6 mg/kg) produces a significant therapeutic effect, which is manifested by
D S Sukhanov et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (1)(1), 65-69 (2013-06-29)
The results of pre-clinical research of cycloferon, remaxol and runihol on the model of experimental generalized tuberculosis, caused by the MBT with a different spectrum of drug sensitivity are presented. A considerable increase of the curative effect of the therapy
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