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Merck
CN

17927

9-Oxo-10(9H)-acridineacetic acid

derivatization grade (HPLC), ≥99.0% (T)

Synonym(s):

(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid, 10-(Carboxymethyl)-9(10H)acridone

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About This Item

Empirical Formula (Hill Notation):
C15H11NO3
CAS Number:
Molecular Weight:
253.25
UNSPSC Code:
12352106
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
227508
Assay:
≥99.0% (T)
Form:
solid
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InChI

1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)

SMILES string

OC(=O)CN1c2ccccc2C(=O)c3ccccc13

InChI key

UOMKBIIXHQIERR-UHFFFAOYSA-N

grade

derivatization grade (HPLC)

assay

≥99.0% (T)

form

solid

mp

~289 °C (dec.)

Quality Level

Application

9-Oxo-10(9H)-acridineacetic acid and its analogs are used to study their potential activity as interferon inducers.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis
Reagent for pre-column derivatization of amino acids for fluorescent determination in HPLC; Building block in pharmaceutics

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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V M Frolov et al.
Likars'ka sprava, (1-2)(1-2), 102-107 (2012-10-06)
The effect of the immunotropic drug cycloferon and herbal medicine resources on the basis of Cynara scolimus L. on the blood cytokine profile in the patients with chronic viral hepatitis C (CVHC) in medical rehabilitation (MR) period. Established that prior
A V Gordeets et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(2), 17-19 (2013-05-02)
The case records of 120 children older than 4 years with rotavirus infection have been studied. In this group, 22 patients received basic therapy and 98 received complex therapy with cycloferon. Appropriate therapy resulted in rapid positive dynamics of clinical
E D Bazhanova
Eksperimental'naia i klinicheskaia farmakologiia, 75(10), 42-46 (2012-12-18)
A detailed analysis of the literature data gives contradictory information about the role of interferon-alpha in the regulation of apoptosis, while there are almost no data on the participation of cycloferon in this process. Results of original experiments in recent
S.A. Lyakhov et al.
Pharmazie, 49, 367-367 (1994)
Competition of sodium salt of 9-oxo-10-acridineacetic acid with analogs during induction of interferon in the mouse bone marrow-derived macrophages.
Szulc B, Inglot AD, Szulc Z, Mlochowski J.
Arch. Immunol. Ther. Exp., 33, 287-297 (1985)

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