17927
9-Oxo-10(9H)-acridineacetic acid
derivatization grade (HPLC), ≥99.0% (T)
Synonym(s):
(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid, 10-(Carboxymethyl)-9(10H)acridone
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About This Item
Empirical Formula (Hill Notation):
C15H11NO3
CAS Number:
Molecular Weight:
253.25
Beilstein:
227508
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.32
grade
derivatization grade (HPLC)
Quality Level
Assay
≥99.0% (T)
form
solid
mp
~289 °C (dec.)
SMILES string
OC(=O)CN1c2ccccc2C(=O)c3ccccc13
InChI
1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)
InChI key
UOMKBIIXHQIERR-UHFFFAOYSA-N
Application
9-Oxo-10(9H)-acridineacetic acid and its analogs are used to study their potential activity as interferon inducers.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Competition of sodium salt of 9-oxo-10-acridineacetic acid with analogs during induction of interferon in the mouse bone marrow-derived macrophages.
Szulc B, Inglot AD, Szulc Z, Mlochowski J.
Arch. Immunol. Ther. Exp., 33, 287-297 (1985)
[Role of cycloferon and interferon-alphain apoptosis regulation in neuroendocrinal system on aging].
E D Bazhanova
Eksperimental'naia i klinicheskaia farmakologiia, 75(10), 42-46 (2012-12-18)
A detailed analysis of the literature data gives contradictory information about the role of interferon-alpha in the regulation of apoptosis, while there are almost no data on the participation of cycloferon in this process. Results of original experiments in recent
S.A. Lyakhov et al.
Pharmazie, 49, 367-367 (1994)
A V Gordeets et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(2), 17-19 (2013-05-02)
The case records of 120 children older than 4 years with rotavirus infection have been studied. In this group, 22 patients received basic therapy and 98 received complex therapy with cycloferon. Appropriate therapy resulted in rapid positive dynamics of clinical
V M Frolov et al.
Likars'ka sprava, (1-2)(1-2), 102-107 (2012-10-06)
The effect of the immunotropic drug cycloferon and herbal medicine resources on the basis of Cynara scolimus L. on the blood cytokine profile in the patients with chronic viral hepatitis C (CVHC) in medical rehabilitation (MR) period. Established that prior
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