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17928

O-Methyl-O′-succinylpolyethylene glycol 2′000

Name: <I>O</I>-Methyl-<I>O</I>′-succinylpolyethylene glycol 2′000
Brand: SIGMA

Synonym(s):

Polyethylene glycol, O-(Succinyl)-O′-methylpolyethylene glycol 2′000, Polyethylene glycol 2′000 monomethyl ether succinate

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About This Item

Linear Formula:

CH₃O(CH₂CH₂O)_nCOCH₂CH₂COOH

CAS Number:

31961-02-1

UNSPSC Code:

51171641

NACRES:

NA.26

MDL number:

MFCD00284260

eCl@ss:

32039090

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Properties

form

powder

Quality Segment

100

mol wt

M_r ~2100

mp

50-53 °C

Ω-end

carboxylic acid

α-end

methoxy

storage temp.

−20°C

Description

Application

Polyethylene glycol 2000 is used in the construction of biomaterials such as biopolymers, micelles and nanostructures.

Biochem/physiol Actions

O-Methyl-O′-succinylpolyethylene glycol 2′000 is a modified monomethoxypolyethylene glycol (mPEG) wherein the hydroxyl groups are succinylated by succinic anhydride. This succinylated mPEG can then be used to synthesize tolerogenic mPEG conjugates of peptides. Tolerogenic peptide conjugates are very effective reagents for obtaining epitope-specific immunosuppression of antibody responses to immunopathogenic sites on multideterminant complex protein antigens.

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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