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17937

25-Hydroxyvitamin D2

≥95.0% (HPLC)

Synonym(s):

25-Hydroxycalciferol, 25-Hydroxyergocalciferol, Ercalcidiol

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About This Item

Empirical Formula (Hill Notation):
C28H44O2
CAS Number:
21343-40-8
Molecular Weight:
412.65
NACRES:
NA.28
PubChem Substance ID:
57647689
eCl@ss:
34058017
UNSPSC Code:
12352205
MDL number:
MFCD02683431
Beilstein/REAXYS Number:
4716773
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biological source

synthetic

Quality Level

200

assay

≥95.0% (HPLC)

form

crystalline powder

color

white

storage temp.

−20°C

SMILES string

[H][C@@]12CC[C@H]([C@H](C)\C=C\[C@H](C)C(C)(C)O)[C@@]1(C)CCC/C2=C\C=C3\C[C@@H](O)CCC3=C

InChI

1S/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12+,23-13-/t20-,21+,24+,25-,26+,28-/m1/s1

InChI key

KJKIIUAXZGLUND-ICCVIKJNSA-N

Biochem/physiol Actions

Ergocalciferol (vitamin D2) is activated in vivo by hydroxylation to 25-hydroxyergocalciferol and 1α,25-dihydroxycalciferol. Activated Vitamin D2 molecules may be used in a wide range of studies to assess their effects on functions such as immune function and calcium homeostasis.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
0000539972
0000539972
0000357799
0000374682
0000343415

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Paul Haggarty et al.
The British journal of nutrition, 109(5), 898-905 (2012-11-22)
The aims of the present study were to determine compliance with current advice on vitamin D and to assess the influence of season, dietary intake, supplement use and deprivation on vitamin D status in pregnant mothers and newborns in the
Kevin D Cashman et al.
The British journal of nutrition, 112(2), 193-202 (2014-05-02)
It has been suggested that vitamin D₂ is not very prevalent in the human food chain. However, data from a number of recent intervention studies suggest that the majority of subjects had measurable serum 25-hydroxyvitamin D₂ (25(OH)D₂) concentrations. Serum 25(OH)D₂
Grant R Campbell et al.
PLoS pathogens, 8(11), e1003017-e1003017 (2012-11-21)
Toll-like receptors (TLR) are important in recognizing microbial pathogens and triggering host innate immune responses, including autophagy, and in the mediation of immune activation during human immunodeficiency virus type-1 (HIV) infection. We report here that TLR8 activation in human macrophages
View All Related Papers

Global Trade Item Number

SKUGTIN
17937-1MG04061838754233