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Sodium propionate

Name: Sodium propionate
Brand: SIGMA

meets analytical specification of NF, 99-100.5% (ex dried subst.)

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Synonym(s):

Propionic acid sodium salt

Linear Formula:

CH₃CH₂COONa

CAS Number:

137-40-6

Molecular Weight:

96.06

Beilstein:

3566934

EC Number:

205-290-4

MDL number:

MFCD00002759

PubChem Substance ID:

57647711

NACRES:

NA.21

Quality Level

200

Assay

99-100.5% (ex dried subst.)

quality

meets analytical specification of NF

impurities

≤0.001% heavy metals (as Pb)
≤1% water (Karl Fischer)

mp

285-286 °C (lit.)

solubility

alcohol: soluble 1 gm in 24 ml at 25 °C
water: soluble 1 gm in 0.65 ml at 25 °C
water: soluble 1 g/mL at 25 °C

cation traces

Fe: ≤30 mg/kg
Zn: ≤10 mg/kg

application(s)

pharmaceutical (small molecule)

lipid type

saturated FAs

SMILES string

[Na+].CCC([O-])=O

InChI

1S/C3H6O2.Na/c1-2-3(4)5;/h2H2,1H3,(H,4,5);/q;+1/p-1

InChI key

JXKPEJDQGNYQSM-UHFFFAOYSA-M

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Propionate may mediate the hypocholesterolemic effects of certain soluble plant fibers in cholesterol-fed rats.

W J Chen et al.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 175(2), 215-218 (1984-02-01)

The effects of propionate on serum and liver lipid concentrations were studied in cholesterol-fed rats. Both serum and liver cholesterol levels were significantly lower in rats fed the cholesterol-propionate diet than in rats fed the cholesterol diet without propionate. Liver

The Stimulatory Effect of Sodium Butyrate and Sodium Propionate on the Development of Rumen Mucosa in the Young Calf.

E.G. Sander

Journal of Dairy Science, 42, 1600-1605 (1959)

Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance.

J McCarthy et al.

Gut, 52(7), 975-980 (2003-06-13)

Prophylactic efficacy against colitis following lactobacillus consumption in interleukin 10 (IL-10) knockout (KO) mice has been reported. Whether this applies equally to other probiotic strains is unknown, and the mechanism is unclear. (1) To compare the effect of feeding Lactobacillus

Inhibition of growth and patulin synthesis in Penicillium expansum by potassium sorbate and sodium propionate in culture.

J E Lennox et al.

Applied and environmental microbiology, 48(5), 1031-1033 (1984-11-01)

Potassium sorbate and sodium propionate brought about a marked inhibition in the growth of Penicillium expansum and a proportionally greater inhibition in the synthesis of patulin by the mold. At inhibitor concentrations used commercially in bakery products, propionate inhibited growth

Measurement of Total and Free Urinary Phenol and Paraben Concentrations over the Course of Pregnancy: Assessing Reliability and Contamination of Specimens in the Norwegian Mother and Child Cohort Study.

Virginia T Guidry et al.

Environmental health perspectives, 123(7), 705-711 (2015-03-18)

Exposures to environmental phenols and parabens may be harmful, especially in utero. Prior studies have demonstrated high within-person variability of urinary concentrations across pregnancy. We sought to measure phenol and paraben biomarker concentrations for the Norwegian Mother and Child Cohort

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