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Merck
CN

18448

N-Stearoyl-D-sphingosine

≥98.0% (TLC)

Synonym(s):

Cer(d18:1/18:0), (2S,3R,4E)-2-(Stearoylamino)-4-octadecene-1,3-diol, N-Octadecanoyl-D-sphingosine, N-Stearoyl-D-erythro-sphingosine, N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]octadecanamide, C18 Ceramide (d18:1/18:0), C18-Ceramide

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About This Item

Empirical Formula (Hill Notation):
C36H71NO3
CAS Number:
2304-81-6
Molecular Weight:
565.95
UNSPSC Code:
12352211
NACRES:
NA.85
PubChem Substance ID:
329751672
MDL number:
MFCD02259139
Beilstein/REAXYS Number:
1717539

Key Documents

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Product Name

N-Stearoyl-D-sphingosine, ≥98.0% (TLC)

InChI

1S/C36H71NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h29,31,34-35,38-39H,3-28,30,32-33H2,1-2H3,(H,37,40)/b31-29+/t34-,35+/m0/s1

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI key

VODZWWMEJITOND-NXCSZAMKSA-N

assay

≥98.0% (TLC)

form

powder or crystals

composition

carbon content, 76.40%
hydrogen content, 12.64%
nitrogen content, 2.47%

functional group

amide

lipid type

sphingolipids

shipped in

wet ice

storage temp.

−20°C

Quality Level

100

Related Categories

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCBX0150
BCBH6550V
BCBH6550

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Emile Zakiev et al.
Journal of clinical lipidology, 13(3), 468-480 (2019-04-21)
Familial apolipoprotein A-I (apoA-I) deficiency (FAID) involving low levels of both apoA-I and high-density lipoprotein (HDL) cholesterol is associated with accelerated atherosclerosis. The objective of this study was to define distinctive patterns in the lipidome of HDL subpopulations in FAID
Alice Gualerzi et al.
Scientific reports, 7(1), 9820-9820 (2017-08-31)
Extracellular vesicles (EVs) from mesenchymal stromal cells (MSC) are emerging as valuable therapeutic agents for tissue regeneration and immunomodulation, but their clinical applications have so far been limited by the technical restraints of current isolation and characterisation procedures. This study
M Mirzaian et al.
Clinica chimica acta; international journal of clinical chemistry, 466, 178-184 (2017-01-17)
Free sphingoid bases (lysosphingolipids) of primary storage sphingolipids are increased in tissues and plasma of several sphingolipidoses. As shown earlier by us, sphingoid bases can be accurately quantified using UPLC-ESI-MS/MS, particularly in combination with identical
Li-Pin Kao et al.
Journal of lipid research, 60(9), 1590-1602 (2019-08-01)
The combination of daunorubicin (dnr) and cytarabine (Ara-C) is a cornerstone of treatment for acute myelogenous leukemia (AML); resistance to these drugs is a major cause of treatment failure. Ceramide, a sphingolipid (SL), plays a critical role in cancer cell
Erik B Watkins et al.
Biophysical journal, 114(5), 1103-1115 (2018-03-15)
The influence of carbohydrate structure on the ordering of glycosphingolipids (GSLs) and surrounding phospholipids was investigated in monolayers at the air-water interface. Binary mixtures composed of GSLs, chosen to span a range of carbohydrate complexity, and zwitterionic dipalmitoylphosphatidylcholine phospholipid, were
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