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Merck
CN

200R-1

Androgen Receptor (SP107) Rabbit Monoclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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isotype

IgG

biological source

rabbit

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

SP107, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (200R-14)
vial of 0.5 mL concentrate (200R-15)
bottle of 1.0 mL predilute (200R-17)
vial of 1.0 mL concentrate (200R-16)
bottle of 7.0 mL predilute (200R-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

control

prostate

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Quality Level

100
500

Related Categories

Other Notes

Androgen Receptor Positive Control Slides, Product No. 200S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Analysis Note


IVD
IVD
IVD
RUO

General description

As a member of the steroid hormone superfamily, androgen receptor functions within distinctintracellular compartments to mediate cellular growth and transcriptional activation ofandrogen-regulated signaling pathways. Androgen receptor expression is broadly distributedacross a variety of normal tissue types. The anti-androgen receptor may be used as an aid toidentify carcinomas of the breast and prostate.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000495481
0000495481
0000444499
0000443142
0000444495

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Laura C Collins et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(7), 924-931 (2011-05-10)
Previous studies have demonstrated that androgen receptor is expressed in many breast cancers, but its expression in relation to the various breast cancer subtypes as defined by molecular profiling has not been studied in detail. We constructed tissue microarrays from
A K Roy et al.
Annals of the New York Academy of Sciences, 949, 44-57 (2002-01-25)
Androgens are C-19 steroids secreted primarily from the testes and adrenals that play a critical role in reproduction. Reproductive functions of androgens are mediated through coordination of diverse physiological processes ranging from brain functions to specific cell proliferation and apoptosis.
R S Carroll et al.
Journal of neurosurgery, 82(3), 453-460 (1995-03-01)
The predominance of meningiomas in females, the accelerated growth of these tumors during the luteal phase of the menstrual cycle and during pregnancy, and the association between meningiomas and breast cancer have led to a number of studies examining the
Carlos Cordon-Cardo et al.
The Journal of clinical investigation, 117(7), 1876-1883 (2007-06-09)
We have developed an integrated, multidisciplinary methodology, termed systems pathology, to generate highly accurate predictive tools for complex diseases, using prostate cancer for the prototype. To predict the recurrence of prostate cancer following radical prostatectomy, defined by rising serum prostate-specific
J M Hakimi et al.
World journal of urology, 14(5), 329-337 (1996-01-01)
Androgen-receptor (AR) gene mutations have been found in clinical prostate cancer, both prior to hormonal therapy and in hormone-refractory disease that persists despite androgen-ablative therapy. Thus, mutations that are present in late-stage disease might arise prior to therapy rather than
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