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205R-1

CD5 (SP19) Rabbit Monoclonal Antibody

Name: CD5 (SP19) Rabbit Monoclonal Antibody
Brand: SIGMA

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

SP19, monoclonal

Application:

IHC (p)

Citations:

Technical Service

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Properties

biological source

rabbit

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

SP19, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (205R-14), vial of 0.5 mL concentrate (205R-15), bottle of 1.0 mL predilute (205R-17), vial of 1.0 mL concentrate (205R-16), bottle of 7.0 mL predilute (205R-18)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... CD5(921)

Description

General description

Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-), especially when combined with CD117 and CK7. Anti-CD5 does not react with granulocytes or monocytes.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

RUO

Other Notes

CD5 Positive Control Slides, Product No. 205S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

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Peripheral T-cell lymphoma with a nodular growth pattern.

Ben Hatano et al.

Pathology international, 52(5-6), 400-405 (2002-07-09)

Peripheral T-cell lymphomas (PTCL) with nodular growth patterns are very rare, with only 17 cases reported previously. Here, we report a case of PTCL with a nodular growth pattern. The patient was an 81-year-old Japanese woman who complained of malaise

CD5+ B lymphocytes.

M T Kasaian et al.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 197(3), 226-241 (1991-07-01)

CD5+ T-cell/histiocyte-rich large B-cell lymphoma.

Chung-Che Chang et al.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 15(10), 1051-1057 (2002-10-16)

CD5 expression in neoplastic large B-cells in T-cell/histiocyte-rich large B-cell lymphoma has not been reported, to the best of our knowledge. Here we describe the first case of CD5+ T-cell/histiocyte-rich large B-cell lymphoma that is well documented by histomorphology, immunohistochemistry

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Global Trade Item Number

SKU	GTIN
205R-18	0841683122388
205R-17	0841683126096
205R-14	0841683122357
205R-15	0841683122364
205R-16	0841683122371