biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
SP19, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (205R-14), vial of 0.5 mL concentrate (205R-15), bottle of 1.0 mL predilute (205R-17), vial of 1.0 mL concentrate (205R-16), bottle of 7.0 mL predilute (205R-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG
control
tonsil
shipped in
wet ice
storage temp.
2-8°C
visualization
membranous
Gene Information
human ... CD5(921)
General description
Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-), especially when combined with CD117 and CK7. Anti-CD5 does not react with granulocytes or monocytes.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
CD5 Positive Control Slides, Product No. 205S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Chung-Che Chang et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 15(10), 1051-1057 (2002-10-16)
CD5 expression in neoplastic large B-cells in T-cell/histiocyte-rich large B-cell lymphoma has not been reported, to the best of our knowledge. Here we describe the first case of CD5+ T-cell/histiocyte-rich large B-cell lymphoma that is well documented by histomorphology, immunohistochemistry
Ben Hatano et al.
Pathology international, 52(5-6), 400-405 (2002-07-09)
Peripheral T-cell lymphomas (PTCL) with nodular growth patterns are very rare, with only 17 cases reported previously. Here, we report a case of PTCL with a nodular growth pattern. The patient was an 81-year-old Japanese woman who complained of malaise
CD5+ B lymphocytes.
M T Kasaian et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 197(3), 226-241 (1991-07-01)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 205R-18 | 0841683122388 |
| 205R-17 | 0841683126096 |
| 205R-14 | 0841683122357 |
| 205R-15 | 0841683122364 |
| 205R-16 | 0841683122371 |