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21879

5(6)-Carboxyfluorescein diacetate

Name: 5(6)-Carboxyfluorescein diacetate
Brand: SIGMA

BioReagent, suitable for fluorescence, ≥90.0% (HPLC)

Synonym(s):

5(6)-Carboxy-di-O-acetylfluorescein

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About This Item

Empirical Formula (Hill Notation):

C₂₅H₁₆O₉

CAS Number:

124387-19-5

Molecular Weight:

460.39

NACRES:

NA.32

PubChem Substance ID:

329752214

UNSPSC Code:

12352108

MDL number:

MFCD00467494

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product line

BioReagent

Quality Level

100

assay

≥90.0% (HPLC)

form

powder

solubility

DMSO: soluble

fluorescence

λ_ex 492 nm; λ_em 517 nm in 0.1 M Tris pH 8.0 (esterase)

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1.CC(=O)Oc6ccc7c(Oc8cc(OC(C)=O)ccc8C79OC(=O)c%10cccc(C(O)=O)c9%10)c6

InChI

1S/2C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25;1-12(26)31-14-6-8-18-20(10-14)33-21-11-15(32-13(2)27)7-9-19(21)25(18)22-16(23(28)29)4-3-5-17(22)24(30)34-25/h2*3-11H,1-2H3,(H,28,29)

InChI key

SWRGCNMDGRMQGB-UHFFFAOYSA-N

Related Categories

Clinical & Diagnostics

Dry Dyes & Certified Stains

Tissue Diagnostics

General description

5(6)-Carboxyfluorescein diacetate or CDFDA is a fluorescent oxidant sensing probe. It is an intracellular probe added to the cells as a pro-substrate, which upon hydrolysis by the esterase enzyme produces the fluorescent product called CDF.

Application

5(6)-Carboxyfluorescein diacetate (CFDA) is a dye which is been extensively utilized to label cultured neurons with the essential requirements, in a specific manner.

5(6)- Carboxyfluorescein diacetate (CFDA) is a viability probe that assesses enzymatic activity, which is necessary to activate its fluorescence, and cell-membrane integrity, which is necessary for the retention of their fluorescent product within the cell.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Global Trade Item Number

SKU	GTIN
21879-25MG-F	04061838775641
21879-100MG-F	04061838775634

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