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Merck
CN

21965

5(6)-Carboxy-X-rhodamine

BioReagent, suitable for fluorescence

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About This Item

Empirical Formula (Hill Notation):
C33H30N2O5
CAS Number:
198978-94-8
Molecular Weight:
534.60
MDL number:
MFCD01862979
UNSPSC Code:
12352116
PubChem Substance ID:
329752228
NACRES:
NA.32

Key Documents

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Product Name

5(6)-Carboxy-X-rhodamine, BioReagent, suitable for fluorescence

SMILES string

OC(=O)c1ccc2c(c1)C(=O)OC23c4cc5CCCN6CCCc(c4Oc7c8CCCN9CCCc(cc37)c89)c56.OC(=O)c%10ccc%11C(=O)OC%12(c%13cc%14CCCN%15CCCc(c%13Oc%16c%17CCCN%18CCCc(cc%12%16)c%17%18)c%14%15)c%11c%10

InChI

1S/2C33H30N2O5/c36-31(37)20-9-10-24-23(15-20)32(38)40-33(24)25-16-18-5-1-11-34-13-3-7-21(27(18)34)29(25)39-30-22-8-4-14-35-12-2-6-19(28(22)35)17-26(30)33;36-31(37)20-9-10-21-24(17-20)33(40-32(21)38)25-15-18-5-1-11-34-13-3-7-22(27(18)34)29(25)39-30-23-8-4-14-35-12-2-6-19(28(23)35)16-26(30)33/h2*9-10,15-17H,1-8,11-14H2,(H,36,37)

InChI key

KLNOCCPJAOCRHF-UHFFFAOYSA-N

product line

BioReagent

mp

≥250 °C (lit.)

fluorescence

λex 570 nm; λem ~595 nm in 0.1 M Tris pH 8.0

suitability

suitable for fluorescence

Quality Level

100

Related Categories

Analysis Note

partially soluble in methanol, 0.1 M Tris pH 8.0

Application

5(6)-Carboxy-X-rhodamine may be used as a fluorescent dye in nucleic acid analytical research applications.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK2755
BCCH2807
BCCH7930
BCCD6949
BCCD5623

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Gadi Cohen et al.
Arteriosclerosis, thrombosis, and vascular biology, 39(8), 1602-1613 (2019-06-14)
The early embryo implantation is characterized by enhanced uterine vascular permeability at the site of blastocyst attachment, followed by extracellular-matrix remodeling and angiogenesis. Two TG (transglutaminase) isoenzymes, TG2 (tissue TG) and FXIII (factor XIII), catalyze covalent cross-linking of the extracellular-matrix.
Jin-Oh You et al.
International journal of nanomedicine, 1(2), 173-180 (2007-08-29)
Reverse microemulsion was used as a template to fabricate chitosan-alginate core-shell nanoparticles encapsulated with enhanced green fluorescent protein (EGFP)-encoded plasmids. The average size of DNA-entrapped nanoparticles measured by dynamic light scattering was increased proportionally, with the N/P ratios ranging from
Tae Seok Seo et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(17), 5926-5931 (2005-04-15)
We report four-color DNA sequencing by synthesis (SBS) on a chip, using four photocleavable fluorescent nucleotide analogues (dGTP-PC-Bodipy-FL-510, dUTP-PC-R6G, dATP-PC-ROX, and dCTP-PC-Bodipy-650) (PC, photocleavable; Bodipy, 4,4-difluoro-4-bora-3alpha,4alpha-diaza-s-indacene; ROX, 6-carboxy-X-rhodamine; R6G, 6-carboxyrhodamine-6G). Each nucleotide analogue consists of a different fluorophore attached to
P J Oefner et al.
Analytical biochemistry, 223(1), 39-46 (1994-11-15)
Using 100 mM of triethylammonium acetate as ion-pairing reagent, phosphodiester oligonucleotides labeled fluorescently at their 5' terminus could be separated successfully on alkylated nonporous 2.3-microns poly(styrene-divinylbenzene) particles by means of high-resolution liquid chromatography. Applying excitation wavelengths of 490, 520, 550
Jun Wang et al.
Clinical chemistry, 56(4), 623-632 (2010-03-09)
The EGFR [epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)] gene is known to harbor genomic alterations in advanced lung cancer involving gene amplification and kinase mutations that predict the clinical response to EGFR-targeted inhibitors. Methods for

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