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227R-2

BCL6 (EP278) Rabbit Monoclonal Primary Antibody

Name: BCL6 (EP278) Rabbit Monoclonal Primary Antibody
Brand: SIGMA

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

EP278, monoclonal

Application:

IHC (p)

Citations:

Technical Service

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Properties

biological source

rabbit

Quality Segment

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP278, monoclonal

description

(For In Vitro Diagnostic Use in Select Regions (See Chart))

form

buffered aqueous solution

species reactivity

human

packaging

bottle of 1.0 mL predilute (227R-27), bottle of 7.0 mL predilute (227R-28), vial of 0.1 mL concentrate (227R-24), vial of 0.5 mL concentrate (227R-25), vial of 1.0 mL concentrate (227R-26), vial of 0.1 mL concentrate Research Use Only (227R-24-RUO), vial of 1.0 mL concentrate Research Use Only (227R-26-RUO), vial of 1.0 mL pre-dilute Research Use Only (227R-27-RUO), vial of 7.0 mL pre-dilute ready-to-use Research Use Only (227R-28-RUO)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... BCL6(604)

Description

General description

BCL6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein.¹ In normal tissue these antibodies have strong nuclear staining for a subset of B-lymphocytes, mostly located in germinal centers (GC).² BCL6 antibodies stain malignant cells in follicular lymphoma,³ diffuse large B-cell lymphomas,⁴ Burkitt lymphoma,⁴ classical Hodgkin lymphoma,⁵ as well as majority of tumor cells in nodular lymphocyte predominant Hodgkin lymphoma.⁶ BCL6 expression has been also seen in anaplastic large cell lymphomas (ALCL).⁷

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

RUO

Other Notes

BCL6 Positive Control Slides, Product No. 227S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c