232R-1
Calretinin (SP13) Rabbit Monoclonal Antibody
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
SP13, monoclonal
Application:
IHC (p)
Citations:
8
biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
SP13, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (232R-14), vial of 0.5 mL concentrate (232R-15), bottle of 1.0 mL predilute (232R-17), vial of 1.0 mL concentrate (232R-16), bottle of 7.0 mL predilute (232R-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
isotype
IgG1
control
mesothelioma
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic, nuclear
General description
Calretinin is a 29 kDa calcium-binding protein thought to play a role in the cell cycle. Anti-calretinin has been shown to be useful in differentiating mesothelioma from adenocarcinomas from the lung and other sources. The sensitivity of anti-calretinin in distinguishing reactive mesothelial cells from adenocarcinoma cells is 100%, and the specificity is up to 80%. Light, focal, cytoplasmic staining of adenocarcinoma cells may be seen in 10 to 30% of cases. Anti-calretinin has also demonstrated utility in differentiating adrenal cortical neoplasms (+) from pheochromocytomas (-). Calretinin has also been useful in diagnosing granulosa cell tumor of the ovary amongst its mimics. Other ovarian tumors that stain with calretinin are Sertoli-Leydig cell tumor, Sertoli cell tumor, Leydig cell tumor, and sex cord tumor with annular tubules, as well as steroid cell tumor.9
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Other Notes
Calretinin Positive Control Slides, Product No. 232S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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