Skip to Content
Merck
CN

235R-1

Sigma-Aldrich

CDX-2 (EPR2764Y) Rabbit Monoclonal Primary Antibody

Sign Into View Organizational & Contract Pricing

Select a Size

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EPR2764Y, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (235R-14)
vial of 0.5 mL concentrate (235R-15)
bottle of 1.0 mL predilute (235R-17)
vial of 1.0 mL concentrate (235R-16)
bottle of 7.0 mL predilute (235R-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG

control

colon

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... CDX2(1045)

Related Categories

General description

CDX-2 is a caudal-related homeobox transcription factor that plays a role in the development and maintenance of intestinal mucosa. This protein is expressed in the normal and neoplastic gastrointestinal epithelium, including colorectal adenocarcinoma. It is useful for identifying the gastrointestinal origin of benign and malignant lesions.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

CDX-2 Positive Control Slides, Product No. 235S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000482018
0000482018
0000441095
0000441095
0000431942

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lori A Erickson et al.
Endocrine pathology, 15(3), 247-252 (2005-01-11)
The transcription factors CDX1 and CDX2 are homeobox genes that regulate development of the epithelium of the small and large intestine. A few studies have shown that Cdx2 protein expression is useful in the diagnosis of adenocarcinomas as well as
Anjali Saqi et al.
American journal of clinical pathology, 123(3), 394-404 (2005-02-18)
Carcinoids of different organs appear morphologically indistinguishable. We studied the usefulness of differential expression of CDX2 and thyroid transcription factor-1 (TTF-1) in 78 gastrointestinal and pulmonary carcinoids and their metastases (n = 10). CDX2 staining of gastric biopsy specimens with
Gabriel M Groisman et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 23(1), 52-57 (2003-12-12)
Histologic differentiation of primary ovarian carcinoma from colonic carcinoma metastatic to the ovary may be difficult. Cytokeratin 7 (CK7) and cytokeratin 20 (CK20) immunostaining is usually used, but these markers lack specificity for ovarian and intestinal epithelium, and overlapping results
Reda S Saad et al.
American journal of clinical pathology, 122(3), 421-427 (2004-09-15)
We studied the diagnostic value of Cdx2 to distinguish mucinous bronchioloalveolar carcinoma from mucinous colorectal adenocarcinoma metastatic to the lung. We retrieved 92 via the hospital computer system, including 30 mucinous bronchioloalveolar carcinomas, 32 nonmucinous bronchioloalveolar carcinomas, and 30 mucinous
Robert W Werling et al.
The American journal of surgical pathology, 27(3), 303-310 (2003-02-27)
CDX2 is a recently cloned homeobox gene that encodes an intestine-specific transcription factor, expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. While expression of CDX2 protein in primary and metastatic colorectal carcinomas has been
View All Related Papers

Articles

Immunohistochemistry Applications in Gastrointestinal Cancer

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

胃肠道癌症中的免疫组织化学应用

结直肠癌是男性和女性中第三大常见癌症。预计2016年将发生136,000例结直肠癌。

Related Content

诊断性免疫组化操作步骤

诊断性免疫组化是一系列用于识别组织异常、建立预后并提示治疗方式的技术。其基本原理是一种抗原-抗体结合反应，利用酶或荧光染料来标记抗体，呈现出组织或组织切片中特定抗原的位置和分布。

Diagnostic Immunohistochemistry Procedures

Diagnostic immunohistochemistry overview highlights its importance in cancer diagnosis and detecting infectious diseases in modern clinical pathology.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service