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Merck
CN

250A-1

Factor VIII-R Ag. Rabbit Polyclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (250A-14)
vial of 0.5 mL concentrate (250A-15)
bottle of 1.0 mL predilute (250A-17)
vial of 1.0 mL concentrate (250A-16)
bottle of 7.0 mL predilute (250A-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:50

control

placenta

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Quality Level

100
500

Gene Information

human ... VWF(7450)

Related Categories

Analysis Note


IVD
IVD
IVD
RUO

General description

Factor VIII-Related Antigen or von Willebrand factor is a glycoprotein associated with hemostasis in promoting the adhesion of platelets. Anti-Factor VIII Related Antigen reactivity is seen in endothelial cells, hemangioma, and the majority of tumors of endothelial origin such as Kaposi’s sarcoma and angiosarcoma.

Other Notes

Factor VIII-R Ag. (polyclonal) Positive Control Slides, Product No. 250S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000515362
0000515362
0000515342
0000515342
0000509482

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T Yamamoto et al.
Pathology international, 46(5), 364-371 (1996-05-01)
The sinusoidal structure and blood supply of 38 liver nodules less than 2 cm in diameter were investigated. There were 18 cases of adenomatous hyperplasia (AH) and 20 cases of hepatocellular carcinoma (HCC). Growth pattern, encapsulation and vascularity were examined
K H Fulling et al.
Cancer, 51(6), 1107-1118 (1983-03-15)
Two cases of neoplastic angioendotheliomatosis are described. Both patients presented with subacute development of dementia punctuated by focal neurologic signs. Postmortem examination in both cases disclosed a vasculocentric distribution of neoplastic cells in many organs. Two characteristic histologic patterns were
Wick MR, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 52, 75A-75A (1985)
J Ansell et al.
Cancer, 50(8), 1506-1512 (1982-10-15)
The case history of a patient with diffuse histiocytic lymphoma and skin lesions characteristic of malignant angioendotheliomatosis is reported. The patient initially responded to aggressive chemotherapy but quickly had a relapse, CNS disease developed, and the patient died one year
U K Zätterström et al.
Head & neck, 17(4), 312-318 (1995-07-01)
The progression of tumor growth requires the recruitment of new blood vessels. It has been suggested that the degree of neovascularization would correlate with clinical prognosis. The purpose of the present study was to ascertain whether tumor vascularization correlated with
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