Skip to Content
Merck
CN

Key Documents

View All Documentation

257M-1

GCDFP-15 (23A3) Mouse Monoclonal Antibody

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
23A3, monoclonal
Application:
IHC (p)
Citations:
4
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

mouse

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

23A3, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (257M-14), vial of 0.5 mL concentrate (257M-15), bottle of 1.0 mL predilute (257M-17), vial of 1.0 mL concentrate (257M-16), bottle of 7.0 mL predilute (257M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotype

IgG2a

control

breast, breast carcinoma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... PIP(5304)

General description

GCDFP-15 is a 15 kD glycoprotein which is localized in the apocrine metaplastic epithelium lining breast cysts and in apocrine glands in the axilla, vulva, eyelid, ear canal, and in salivary glands. Approximately 70% of breast carcinomas are labeled with antibody to GCDFP-15. Colorectal carcinomas, lung carcinoma, mesothelimas rarely stain with this antibody. Because of its specificity for breast carcinoma (up to 99%), this antibody is often used in a screening panel in the appropriate clinical situation, often for a woman with metastasis of unknown primary.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
GCDFP-15 Positive Control Slides, Product No. 257S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Still not finding the right product?

Try our Product Selector Tool to narrow your options

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

Regulatory Information

监管及禁止进口产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000517390
0000517390
0000466467
0000466467
0000466468

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

免疫组织化学：目前在乳腺癌中的应用

免疫组织化学（免疫组化，IHC）用于表征所有组织中的细胞内蛋白质或各种细胞表面。个体标记，或更常用的各种标记蛋白质组，可用于表征各种肿瘤亚型，确定原发组织，区分转移性肿瘤和原发性肿瘤，并提供可能对预后有重要意义、预测对治疗的响应、或评估残留肿瘤后处理的其他信息。

Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 227-228 (2014)
A H Ormsby et al.
Journal of the American Academy of Dermatology, 32(5 Pt 1), 711-716 (1995-05-01)
For accurate classification of cutaneous metastatic carcinoma, reliable tumor-specific immunohistochemical markers would be valuable. Our purpose was to analyze the sensitivity, specificity, and positive predictive value of gross cystic disease fluid protein-15 (GCDFP-15) and estrogen receptor protein (ERP) for diagnosing
P Viacava et al.
Virchows Archiv : an international journal of pathology, 432(3), 255-260 (1998-04-09)
GCDFP-15, a glycoprotein identified in the cyst fluid of cystic breast disease, is considered to be a marker of apocrine differentiation. Studies on GCDFP-15 localization in adult normal tissues are lacking, and no information on GCDFP-15 expression during fetal development
View All Related Papers

Global Trade Item Number

SKUGTIN
257M-140841683130796
257M-150841683130802
257M-180841683130833
257M-170841683130826
257M-16-RUO04061836529734
257M-160841683130819