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Merck
CN

259A-1

Glucagon Rabbit Polyclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p)
Citations:
5
Technical Service
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (259A-14), vial of 0.5 mL concentrate (259A-15), bottle of 1.0 mL predilute (259A-17), vial of 1.0 mL concentrate (259A-16), bottle of 7.0 mL predilute (259A-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

control

pancreas

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... GCG(2641)

General description

The normal islets of Langerhans (pancreas) contain four major cell types, 15-20% of which are alpha cells which produce glucagon. Alpha cell tumors can be divided into two distinct types; those associated with glucagonoma syndrome (necrolytic migratory erythema, diabetes, anemia, stomatitis, weight loss, venous thromboses, diarrhea, and sometimes psychiatric disturbances), and those which are not. Those associated with the syndrome tend to be large and solitary and there is a high incidence of malignancy. Those glucagonomas not associated with the syndrome tend to be multiple and small and are nearly always benign.Immunohistochemically, the two types of glucagonoma are reactive to the glucagon antibody, though occasionally only weakly.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Glucagon (polyclonal) Positive Control Slides, Product No. 259S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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