26004K
MAPTrix™ Adhesive
High Molecular Weight, Tyrosinase-Pretreated, lyophilized powder, suitable for cell culture
Synonym(s):
MAPTrix™ Technology
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.75
Form:
lyophilized powder
Technique(s):
cell culture | mammalian: suitable
Mol wt:
~37 kDa
Assay:
>90% (SDS-PAGE)
Product Name
MAPTrix™ Adhesive, High Molecular Weight, Tyrosinase-Pretreated, lyophilized powder
sterility
sterile
assay
>90% (SDS-PAGE)
form
lyophilized powder
mol wt
~37 kDa
packaging
pkg of 100 mg, pkg of 5 mg
technique(s)
cell culture | mammalian: suitable
solubility
PBS: soluble, water: soluble
shipped in
ambient
storage temp.
2-8°C
General description
MAPTrix™ Reagent intended for use as a protein, cell, or tissue adhesive.
Application
MAPTrix™ Technology provides a true extracellular microenvironment (ECM) by presenting combinatorial peptide motifs. The ECM, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions.Currently existing technology offers simple and merely adequate environments that facilitate simple cell processes such as cellular adhesion. The simple presentation of cell adhesion motifs is not optimal for controlling more integrated processes. Crosstalk among signaling pathways act synergistically to enhance cellular responses such as cell adhesion or proliferation. A study showed that a combination of extracellular matrix derived peptides presented on a surface may enhance cell adhesion strength and focal adhesion assembly. The combinatorial presentation of ECM peptides on cell growth surfaces may also promote elevated proliferation rates of primary or stem cells.
Features and Benefits
- Biochemically-defined, animal-free cell culture surfaces designed to enhance cell performance
- MAPTrix™ produces a uniform ECM surface that provides a highly controlled 2D extracellular microenvironment for cell cultures and related applications
- Adhesion properties of the mussel adhesive protein makes the coating reproducible & reliable
Legal Information
MAPTrix is a trademark of Kollodis Biosciences
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Storage Class
11 - Combustible Solids
wgk
WGK 3
Regulatory Information
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S J Fashena et al.
Nature cell biology, 2(12), E225-E229 (2001-01-09)
Over the past twenty years, intensive research has enabled us to identify components of specific signalling pathways downstream of an array of adhesion and growth-factor receptors. The first Gordon Research Conference on 'Signalling by Adhesion Receptors', which took place in
Seung Tae Lee et al.
Biomaterials, 31(6), 1219-1226 (2009-11-21)
We present development and use of a 3D synthetic extracellular matrix (ECM) analog with integrin-specific adhesion ligands to characterize the microenvironmental influences in embryonic stem cell (ESC) self-renewal. Transcriptional analysis of 24 integrin subunits followed by confirmation at the translational
Samuel Schmidt et al.
Cell and tissue research, 339(1), 83-92 (2009-11-19)
Adhesion and migration are integrated cell functions that build, maintain and remodel the multicellular organism. In migrating cells, integrins are the main transmembrane receptors that provide dynamic interactions between extracellular ligands and actin cytoskeleton and signalling machineries. In parallel to
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 26004K-5MG | 04061832951225 |
| 26004K-100MG | 04061826081914 |