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272M-1

INI-1 (MRQ-27) Mouse Monoclonal Antibody

Name: INI-1 (MRQ-27) Mouse Monoclonal Antibody
Brand: SIGMA

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

MRQ-27, monoclonal

Application:

IHC (p)

Citations:

Technical Service

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Properties

biological source

mouse

Quality Segment

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

MRQ-27, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (272M-14), vial of 0.5 mL concentrate (272M-15), bottle of 1.0 mL predilute (272M-17), vial of 1.0 mL concentrate (272M-16), bottle of 7.0 mL predilute (272M-18)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

control

brain, endothelial cells

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... SMARCB1(6598)

Description

General description

INI-1, also known as SMARCB1, is one of the core subunit proteins of the ATP-dependent SWI/SNF chromatin remodeling complex. It is involved in chromatin remodeling and transcriptional regulation and functions as a tumor suppressor. Nuclear INI-1 expression is seen in virtually all normal human tissues and most malignancies but the INI-1 gene is often mutated or deleted in malignant rhabdoid tumors (MRT), including those arising in the central nervous system, leading to a lack of INI-1 expression.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

INI-1 Positive Control Slides, Product No. 272S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number

0000544612

0000539855