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280C-1

Mammaglobin Cocktail (304-1A5 & 31A5)

Mouse & Rabbit Cocktail Antibody

Synonym(s):

Mammaglobin Cocktail (304-1A5 & 31A5) Mouse/Rabbit Monoclonal Antibodies

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
304-1A5/31A5, monoclonal
Application:
IHC
Citations:
6
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Quality Level

100, 300, 500

biological source

mouse, rabbit

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

304-1A5/31A5, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart).

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (280C-14-ASR), vial of 0.5 mL concentrate (280C-15-ASR), bottle of 1.0 mL predilute (280C-17-ASR), vial of 1.0 mL concentrate (280C-16-ASR), bottle of 7.0 mL predilute (280C-18-ASR)

concentration

0.01-1 μg/mL (predilute), 2-270 μg/mL (concentrate)

technique(s)

immunohistochemistry: 1:100-1:500

isotype

IgG1, IgG

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... SCGB2A2(4250)

General description

Mammaglobin (10 kD) is a breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin mRNA is present in high levels in human breast cancer cell lines, which has been shown to be a sensitive marker of breast cancer. When combined with other breast-restricted markers such as GCDFP-15, an overall sensitivity for breast carcinoma of 84% has been achieved. Anti-Mammaglobin can also be used to determine breast origin in the setting of metastatic carcinoma.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

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Analysis Note


IVD
IVD
IVD
RUO

Other Notes

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Regulatory Information

常规特殊物品
低风险生物材料

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Articles

免疫组织化学：目前在乳腺癌中的应用

免疫组织化学（免疫组化，IHC）用于表征所有组织中的细胞内蛋白质或各种细胞表面。个体标记，或更常用的各种标记蛋白质组，可用于表征各种肿瘤亚型，确定原发组织，区分转移性肿瘤和原发性肿瘤，并提供可能对预后有重要意义、预测对治疗的响应、或评估残留肿瘤后处理的其他信息。

Zhiqiang Wang et al.
International journal of clinical and experimental pathology, 2(4), 384-389 (2009-01-23)
Identification of metastasis and occult micrometastases of breast cancer demands sensitive and specific diagnostic markers. In this study, we assessed the utility of a mouse monoclonal antibody to human mammaglobin for one such purpose. Immunohistochemical stains were performed on paraffin-embedded
Jae-Ho Han et al.
Archives of pathology & laboratory medicine, 127(10), 1330-1334 (2003-10-03)
Organ specificity is a desirable property of a tumor marker, especially in metastatic adenocarcinomas of unknown primary origin. Mammaglobin, a mammary-specific member of the uteroglobin family, is known to be overexpressed in human breast cancer. We investigated mammaglobin A expression
Rohit Bhargava et al.
American journal of clinical pathology, 127(1), 103-113 (2006-12-06)
There are limited data that compare the usefulness of mammaglobin with gross cystic disease fluid protein-15 (GCDFP-15) in the identification of breast carcinomas. Whole tissue sections of 29 breast carcinomas with matched lymph node metastases and 63 breast carcinomas on
View All Related Papers

Global Trade Item Number

SKUGTIN
280C-15-RUO0841683132592
280C-16-RUO0841683132615
280C-18-RUO0841683132653
280C-18-ASR04061836595272
280C-17-RUO0841683132639
280C-14-RUO0841683132578