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Merck
CN

280R-1

Mammaglobin (31A5) Rabbit Monoclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Technical Service
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biological source

rabbit

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

31A5, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (280R-14)
vial of 0.5 mL concentrate (280R-15)
bottle of 1.0 mL predilute (280R-17)
vial of 1.0 mL concentrate (280R-16)
bottle of 7.0 mL predilute (280R-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG

control

breast carcinoma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Quality Level

100
500

Gene Information

human ... SCGB2A2(4250)

Related Categories

Analysis Note


IVD
IVD
IVD
RUO

General description

Mammaglobin is a breast-associated glycoprotein distantly related to the secretoglobin family that includes human uteroglobin and lipophilin. Anti-mammaglobin labels cytoplasm of normal breast and sweat gland epithelial cells. Its expression is also demonstrated in primary and metastatic breast carcinomas.. The absence of mammaglobin expression is typically seen in the prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Mammaglobin Positive Control Slides , Product No. 280S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000495428
0000494522
0000495427
0000495427
0000495428

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Zhiqiang Wang et al.
International journal of clinical and experimental pathology, 2(4), 384-389 (2009-01-23)
Identification of metastasis and occult micrometastases of breast cancer demands sensitive and specific diagnostic markers. In this study, we assessed the utility of a mouse monoclonal antibody to human mammaglobin for one such purpose. Immunohistochemical stains were performed on paraffin-embedded
Jae-Ho Han et al.
Archives of pathology & laboratory medicine, 127(10), 1330-1334 (2003-10-03)
Organ specificity is a desirable property of a tumor marker, especially in metastatic adenocarcinomas of unknown primary origin. Mammaglobin, a mammary-specific member of the uteroglobin family, is known to be overexpressed in human breast cancer. We investigated mammaglobin A expression
T P Fleming et al.
Annals of the New York Academy of Sciences, 923, 78-89 (2001-02-24)
The mammaglobin gene encodes a 10-kDa glycoprotein that is distantly related to a family of proteins that includes rat estramustine binding protein (EMBP)/prostatein and human Clara cell 10-kDa protein (CC10)/uteroglobin. Among normal adult tissues, mammaglobin mRNA expression has been detected
Eiichi Sasaki et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 20(2), 208-214 (2006-12-29)
Previously, we used the reverse transcription-polymerase chain reaction (RT-PCR) to show that mammaglobin (MGB1) can serve as a differential marker of breast cancer metastasis from primary lung cancer. However, mRNA-based methods are not appropriate for use in clinical practices. In
Rohit Bhargava et al.
American journal of clinical pathology, 127(1), 103-113 (2006-12-06)
There are limited data that compare the usefulness of mammaglobin with gross cystic disease fluid protein-15 (GCDFP-15) in the identification of breast carcinomas. Whole tissue sections of 29 breast carcinomas with matched lymph node metastases and 63 breast carcinomas on
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