Skip to Content
Merck
CN

30058

Lipase Substrate

≥95% (HPLC)

Synonym(s):

1,2-Di-O-lauryl-rac-glycero-3-(glutaric acid 6-methylresorufin ester)

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C45H69NO8
CAS Number:
195833-46-6
Molecular Weight:
752.03
NACRES:
NA.83
PubChem Substance ID:
57648405
UNSPSC Code:
12352204
MDL number:
MFCD08276995

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Lipase Substrate, ≥95% (HPLC)

InChI key

FYOMYGYHAZESGQ-UHFFFAOYSA-N

SMILES string

CCCCCCCCCCCCOCC(COC(=O)CCCC(=O)Oc1ccc2N=C3C=CC(=O)C(C)=C3Oc2c1)OCCCCCCCCCCCC

InChI

1S/C45H69NO8/c1-4-6-8-10-12-14-16-18-20-22-31-50-34-38(51-32-23-21-19-17-15-13-11-9-7-5-2)35-52-43(48)25-24-26-44(49)53-37-27-28-39-42(33-37)54-45-36(3)41(47)30-29-40(45)46-39/h27-30,33,38H,4-26,31-32,34-35H2,1-3H3

assay

≥95% (HPLC)

form

powder

solubility

ethanol: soluble (10mg/mL)

fluorescence

λex 529 nm; λem 600 nm in 0.1 M Tris pH 8.4

storage temp.

2-8°C

Quality Level

100

Application

Lipase Substrate is used as substrate in a high‑throughput screening assay to measure the lipase activity in response to lipstatin production

General description

Lipase substrate (1,2-Di-O-lauryl-rac-glycero-3-(glutaric,acid 6-methylresorufin) ester, DGGR) is a chromogenic substrate for lipases. It is used in colorimetric methods to measure lipase activity. This substrate produces a red-purple compound, methylresorufin, upon digestion by the lipase enzyme.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCM8479
BCCK8939
BCCJ0198
BCCF2452
BCCC9804

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ievgeniia Ostrov et al.
Food microbiology, 82, 316-324 (2019-04-28)
Biofilm-forming Bacillus species are often involved in contamination of dairy products and therefore present a major microbiological challenge in the field of food quality and safety. In this study, we sequenced and analyzed the genomes of milk- and non-milk-derived Bacillus
Alexis Wilkerson et al.
Current microbiology, 77(12), 3937-3944 (2020-10-05)
Microbial assemblages in terrestrial environments, such as soils, utilize hydrolytic enzymes to function biologically in various environments including for the degradation of organic carbon compounds and cycling of nutrients that eventually contributes to the ecological and agricultural productivity of such
Sébastien Cadau et al.
International journal of molecular sciences, 23(21) (2022-11-12)
Atopic dermatitis (AD), the most common inflammatory skin disorder, is a multifactorial disease characterized by a genetic predisposition, epidermal barrier disruption, a strong T helper (Th) type 2 immune reaction to environmental antigens and an altered cutaneous microbiome. Microbial dysbiosis
Michal Híreš et al.
Current microbiology, 75(5), 580-587 (2017-12-20)
Pancreatic lipase inhibitors, such as tetrahydrolipstatin (orlistat), are used in anti-obesity treatments. Orlistat is the only anti-obesity drug approved by the European Medicines Agency (EMA). The drug is synthesized by saturation of lipstatin, a β-lactone compound, isolated from Streptomyces toxytricini
Jose Iglesias et al.
Journal of lipid research, 57(1), 131-141 (2015-10-02)
Lipids are used as cellular building blocks and condensed energy stores and also act as signaling molecules. The glycerolipid/ fatty acid cycle, encompassing lipolysis and lipogenesis, generates many lipid signals. Reliable procedures are not available for measuring activities of several
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service