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Merck
CN

3018

Transcreener® UDP2 FP Assay

Synonym(s):

Transcreener assay

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About This Item

NACRES:
NA.84
UNSPSC Code:
41122100
Storage temp.:
−20°C
Shipped in:
dry ice
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shipped in

dry ice

storage temp.

−20°C

General description

The Transcreener® UDP2 FP Assay is a universal biochemical HTS assay for enzymes that produce UDP, including glycosyltransferase, galactosyltransferase, glucuronyltransferase, N-acetylglucosamyltransferase, N-acetlygalactosyltransferase, xylosyltransferase, and glycogen, cellulose, lactose and hyaluronan synthases. Enzyme activity is signaled by a decrease in fluorescence polarization as the bound tracer is displaced from the Transcreener® UDP2 Antibody. The assay is a simple single step mix-and-read format enabling the use of unmodified native substrate concentrations of 1 – 1000 μM. The assay provides excellent signal at low substrate conversion, with a Z′ =0.7 and =100 millipolarization shift (mP) under normal reaction conditions.

View full Transcreener® product list

Physical form

Kit with buffered aqueous solutions

Preparation Note

3018-1K = 1,000 assay, 384-well
3018-10K = 10,000 assay, 384-well

Legal Information

Transcreener is a registered trademark of BellBrook Labs


Regulatory Information

低风险生物材料
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Traci E Battle et al.
Blood, 102(8), 3016-3024 (2003-07-12)
Bryostatin 1 is known to exhibit in vitro and in vivo activity against chronic lymphocytic leukemia (CLL) cells by inducing their further maturation into plasma-like cells. Signal transducer and activator of transcription (STAT) proteins play a central role in B-lymphocyte
Dennis S Metselaar et al.
EBioMedicine, 50, 81-92 (2019-11-19)
Pediatric high-grade gliomas (pHGG) are the leading cause of cancer-related death during childhood. Due to their diffuse growth characteristics, chemoresistance and location behind the blood-brain barrier (BBB), the prognosis of pHGG has barely improved in the past decades. As such



Global Trade Item Number

SKUGTIN
185493-100G04061836825539
820982100004022536471037
820982025004022536471020
185493-25G04061838757265
3018-1K04061835356874
3018-10K04061835357093