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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

AE1, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (301M-14)
vial of 0.5 mL concentrate (301M-15)
bottle of 1.0 mL predilute (301M-17)
vial of 1.0 mL concentrate (301M-16)
bottle of 7.0 mL predilute (301M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

prostate

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... KRT1(3848)

General description

Anti-cytokeratin, low molecular weight (AE1) labels most acidic keratins; therefore, it is a broadly reactive antibody staining most epithelia and their neoplasms. Members of the acidic and basic cytokeratin subfamilies are found together in pairs; each epithelium contains at least one acidic and one basic keratin so this antibody can show the distribution of keratin containing cells in epithelia. This antibody has shown great sensitivity and broad specificity for keratins under various conditions of fixation and staining. Anti-low molecular weight cytokeratin (AE1) is particularly suited to distinguish poorly differentiated carcinomas from non-epithelial neoplasms. This marker stains both normal and neoplastic cells of epithelial origin.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

Cytokeratin, LMW Positive Control Slides, Product No. 301S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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