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Merck
CN

302M-1

Neurofilament (2F11) Mouse Monoclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
2F11, monoclonal
Application:
IHC (p)
Citations:
8
Technical Service
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

2F11, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (302M-14), vial of 0.5 mL concentrate (302M-15), bottle of 1.0 mL predilute (302M-17), vial of 1.0 mL concentrate (302M-16), bottle of 7.0 mL predilute (302M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

brain

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... NEFL(4747)

General description

Anti-neurofilament stains an antigen localized in a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Neurofilament Positive Control Slides, Product No. 302S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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Regulatory Information

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Protease inhibitors of human plasma. Alpha 1-antichymotrypsin.
R W Berninger
Journal of medicine, 16(1-3), 101-128 (1985-01-01)
S R Dubovy et al.
The British journal of ophthalmology, 85(8), 949-951 (2001-07-24)
Palisaded encapsulated neuroma of the skin (PEN) is an uncommon benign neural tumour that occurs on the head and neck, including the eyelid, but is unfamiliar to many ophthalmic clinicians. For the first time in the ophthalmic literature, the clinical
G N van Muijen et al.
The American journal of pathology, 116(3), 363-369 (1984-09-01)
Three monoclonal antibodies, one directed against cytokeratin (clone 80) and two directed against neurofilament (clones 2F11 and 3G6), were used in the study of a series of 77 lung carcinomas by immunohistochemical staining. The anti-cytokeratin antibody, a very broadly reacting



Global Trade Item Number

SKUGTIN
302M-170841683134381
302M-16-RUO04061836544102
302M-180841683134398
302M-160841683134374
302M-150841683134367
302M-140841683134350