30312
Nα-Methyl-L-lysine monohydrochloride
≥98.0% (TLC)
Synonym(s):
(S)-6-Amino-2-(methylamino)hexanoic acid hydrochloride, N-Me-Lys-OH · HCl
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About This Item
Empirical Formula (Hill Notation):
C7H16N2O2 · HCl
CAS Number:
Molecular Weight:
196.68
UNSPSC Code:
12352202
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6118109
InChI key
LWUKQYOOMILVOV-RGMNGODLSA-N
SMILES string
Cl.CN[C@@H](CCCCN)C(O)=O
InChI
1S/C7H16N2O2.ClH/c1-9-6(7(10)11)4-2-3-5-8;/h6,9H,2-5,8H2,1H3,(H,10,11);1H/t6-;/m0./s1
assay
≥98.0% (TLC)
optical activity
[α]/D 27.5±1.5°, c = 0.1 in 1 M HCl
Quality Level
Biochem/physiol Actions
Nα-Methyl-L-lysine was shown to inhibit the growth and sporulation of Penicillium chrysogenum.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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C G Friedrich et al.
Applied and environmental microbiology, 34(6), 706-709 (1977-12-01)
Compounds structurally related to lysine were tested against Penicillium chrysogenum Wis. 54-1255 for inhibition of growth, sporulation, and penicillin formation. This strain is relatively resistant to lysine analogs. The compounds that were the more active inhibitors of growth and whose
D J Gordon et al.
Biochemistry, 40(28), 8237-8245 (2001-07-11)
A potential goal in the prevention or therapy of Alzheimer's disease is to decrease or eliminate neuritic plaques composed of fibrillar beta-amyloid (Abeta). In this paper we describe N-methyl amino acid containing congeners of the hydrophobic "core domain" of Abeta
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