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Merck
CN

317R-1

Cytokeratin 17 (EP98) Rabbit Monoclonal Primary Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
EP98, monoclonal
Application:
IHC (p)
Citations:
2
Technical Service
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP98, monoclonal

description

(For In Vitro Diagnostic Use in Select Regions (See Chart))

form

buffered aqueous solution

species reactivity

human

packaging

bottle of 1.0 mL predilute (317R-17), bottle of 7.0 mL predilute (317R-18), vial of 0.1 mL concentrate (317R-14), vial of 0.5 mL concentrate (317R-15), vial of 1.0 mL concentrate (317R-16)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotype

IgG

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... KRT17(3872)

General description

Cytokeratin 17 is 46 kD intermediate filament found in simple epithelia and is a marker for cervical reserve (stem) cells.1,2 CK17 can be useful in the identification of uterine cervical squamous lesions including atypical immature metaplasia, cervical intraepithelial neoplasia, and cervical squamous carcinoma.1-3 CK17 also assists in the differentiation of oral squamous cell carcinoma.4

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

Cytokeratin 17 Positive Control Slides, Product No. 317S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

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Luisa F Escobar-Hoyos et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 27(4), 621-630 (2013-09-21)
Most previously described immunohistochemical markers of cervical high-grade squamous intraepithelial lesion (HSIL) and squamous cell carcinoma may help to improve diagnostic accuracy but have a minimal prognostic value. The goals of the current study were to identify and validate novel
Ryoji Kitamura et al.
Journal of cancer research and clinical oncology, 138(8), 1299-1310 (2012-04-03)
The aim of this study was to confirm the expression profile of cytokeratin (CK)17 in comparison with that of CK13 in oral squamous cell carcinoma (OSCC) and leukoplakia and to clarify an association of CK17 with the OSCC differentiation. The



Global Trade Item Number

SKUGTIN
317R-16-RUO04061836605346
317R-160841683121169
317R-18-RUO04061836596224
317R-140841683135449
317R-14-RUO04061826692363
317R-15-RUO04061836605339
317R-170841683121176
317R-180841683121183
317R-150841683135456
317R-17-RUO04061836596217