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333M-1

Spectrin (RBC2/3D5) Mouse Monoclonal Antibody

Name: Spectrin (RBC2/3D5) Mouse Monoclonal Antibody
Brand: SIGMA

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

RBC2/3D5, monoclonal

Application:

IHC (p)

Citations:

Technical Service

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biological source

mouse

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

RBC2/3D5, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (333M-14), vial of 0.5 mL concentrate (333M-15), bottle of 1.0 mL predilute (333M-17), vial of 1.0 mL concentrate (333M-16), bottle of 7.0 mL predilute (333M-18)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:100

isotype

IgG1κ

control

bone marrow

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... SPTA1(6708)

Related Categories

Cell Marque

Cell Marque™ Primary Antibodies

Clinical & Diagnostics

General description

Spectrin is a cytoskeletal protein which is found in muscles, red blood cells and red cell precursors. Anti-Spectrin antibody is useful in the diagnosis of erythroid leukemias.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Spectrin Positive Control Slides, Product No. 333S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

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Different sequences of expression of band 3, spectrin, and ankyrin during normal erythropoiesis and erythroleukemia.

V Nehls et al.

The American journal of pathology, 142(5), 1565-1573 (1993-05-01)

Expression of the erythrocyte anion exchanger band 3, and ankyrin and spectrin, two cytoskeletal proteins of the red blood cell membrane, was studied by immunofluorescence using: 1) smears of human bone marrow from healthy donors and from a patient with

Immunohistological demonstration of erythroid cells in canine bone marrow.

M Müller et al.

Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 48(1), 51-57 (2001-08-23)

In an immunohistological/cytological study of canine bone marrow, the aim was to demonstrate canine erythroid cells with the help of various commercially available antibodies against human antigens (monoclonal antibody against glycophorin A, polyclonal antibodies against haemoglobin and spectrin). In order

An immunocytochemical study of changes in the human erythrocyte membrane skeleton produced by stretching examined by the quick-freezing and deep-etching method.

N Terada et al.

Journal of anatomy, 190 ( Pt 3), 397-404 (1997-04-01)

A quick-freezing and deep-etching method in combination with erythrocyte splitting was used to examine the cytoplasmic aspect of whole-mount human erythrocyte membranes. Various external forces induced alterations in membrane skeletal organisation during the splitting procedure. The initial change was elongation

Immunohistochemical identification of erythroid precursors in paraffin embedded bone marrow sections: spectrin is a superior marker to glycophorin.

Y Sadahira et al.

Journal of clinical pathology, 52(12), 919-921 (2000-03-11)

To investigate whether spectrin can be used as an immunohistochemical marker for erythroid precursors in routinely processed paraffin embedded bone marrow sections. Bone marrow biopsies and clot sections were stained with rabbit antihuman erythrocyte spectrin antibodies, specific for erythroid cells

Global Trade Item Number

SKU	GTIN
333M-16-RUO	04061836532444
333M-18	0841683136682
333M-16	0841683136668
333M-14	0841683136644
333M-17	0841683136675
333M-15	0841683136651

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